SCHEMBL28077679

SCHEMBL28077679

O=C1OC(=O)c2cc(C3=NCCS3)ccc21

nearest known ligand 0.49

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
ALDH1A1 P00352 2/20 0.37
MAPT P10636 1/20 0.37
ATM Q13315 1/20 0.37
ALOX15 P16050 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
NPC1 O15118 1/20 0.36
CASP3 P42574 1/20 0.36
RAB9A P51151 1/20 0.36
SENP8 Q96LD8 1/20 0.36
SENP7 Q9BQF6 1/20 0.36
SENP6 Q9GZR1 1/20 0.36
MGLL Q99685 3/20 0.35
MAP3K5 Q99683 1/20 0.32
HTT P42858 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5017018 0.79 PRF1 (0.56) LMNASMN1; SMN2MAPT
SCHEMBL29358248 0.74 ALOX15 (0.57) LMNASMN1; SMN2ALDH1A1MAPTATM
SCHEMBL29359977 0.74 ALOX15 (0.57) LMNASMN1; SMN2ALDH1A1MAPTATM
SCHEMBL29423347 0.74 ALOX15 (0.57) LMNASMN1; SMN2ALDH1A1MAPTATM
SCHEMBL169305 0.74 ALOX15 (0.57) LMNASMN1; SMN2ALDH1A1MAPTATM
SCHEMBL741462 0.74 ALOX15 (0.57) LMNASMN1; SMN2ALDH1A1MAPTATM
SCHEMBL308376 0.72 ALOX15 (0.55) LMNASMN1; SMN2ALDH1A1MAPTATM
SCHEMBL15641977 0.72 ALOX15 (0.55) LMNASMN1; SMN2ALDH1A1MAPTATM
SCHEMBL17192488 0.72 ALOX15 (0.55) LMNASMN1; SMN2ALDH1A1MAPTATM
SCHEMBL29366467 0.72 ALOX15 (0.55) LMNASMN1; SMN2ALDH1A1MAPTATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102902160-B Colored solidification resin composition 住友化学株式会社 2017-04-12 CN disclosed
CN-102749806-B Colored curable resin composition 住友化学株式会社 2016-10-26 CN disclosed
CN-105842986-A Coloring photosensitive resin composition 住友化学株式会社 2016-08-10 CN disclosed
CN-105842984-A Coloring photosensitive resin composition 住友化学株式会社 2016-08-10 CN disclosed
CN-102681346-B Photosensitive composition 住友化学株式会社 2016-08-03 CN disclosed