SCHEMBL308376

SCHEMBL308376

O=C1OC(=O)c2cc(-c3ccc(-c4ccc5c(c4)C(=O)OC5=O)cc3)ccc21

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
ALDH1A1 P00352 1/20 0.50
MEN1 O00255 1/20 0.48
APAF1 O14727 1/20 0.48
NPC1 O15118 1/20 0.48
LMNA P02545 1/20 0.48
MAPT P10636 1/20 0.48
THRB P10828 1/20 0.48
XBP1 P17861 1/20 0.48
PTBP1 P26599 1/20 0.48
HTT P42858 1/20 0.48
RAB9A P51151 1/20 0.48
GALK1 P51570 1/20 0.48
BLM P54132 1/20 0.48
SMAD3 P84022 1/20 0.48
KMT2A Q03164 1/20 0.48
ATM Q13315 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
NPSR1 Q6W5P4 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15641977 1.00 ALOX15 (0.55) ALOX15TDP1ALDH1A1MEN1APAF1
SCHEMBL17192488 1.00 ALOX15 (0.55) ALOX15TDP1ALDH1A1MEN1APAF1
SCHEMBL29366467 1.00 ALOX15 (0.55) ALOX15TDP1ALDH1A1MEN1APAF1
SCHEMBL29359977 0.97 ALOX15 (0.57) ALOX15TDP1ALDH1A1MEN1APAF1
SCHEMBL29358248 0.97 ALOX15 (0.57) ALOX15TDP1ALDH1A1MEN1APAF1
SCHEMBL169305 0.97 ALOX15 (0.57) ALOX15TDP1ALDH1A1MEN1APAF1
SCHEMBL741462 0.97 ALOX15 (0.57) ALOX15TDP1ALDH1A1MEN1APAF1
SCHEMBL29423347 0.97 ALOX15 (0.57) ALOX15TDP1ALDH1A1MEN1APAF1
SCHEMBL327855 0.93 MEN1 (0.59) ALOX15TDP1ALDH1A1MEN1APAF1
SCHEMBL30821965 0.93 MEN1 (0.59) ALOX15TDP1ALDH1A1MEN1APAF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 140 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240110012-A1 THERMALLY CROSSLINKABLE LIQUID-CRYSTALLINE CO-POLYIMIDES DERIVED FROM WHOLLY AROMATIC DIAMINES AND MULTIPLE MESOGENIC DIANHYDRIDES AND THEIR CROSSLINKED PRODUCTS THEREFROM THE GOVERNMENT OF THE UNITED STATES AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE 2024-04-04 US disclosed
CN-117105892-A Synthesis method of 3,4,3 ', 4' -p-terphenyl tetracarboxylic dianhydride 大连新阳光材料科技有限公司 2023-11-24 CN disclosed
US-11806661-B2 Polymer and method for producing the same, gas separation membrane, gas separation module, and gas separation apparatus using the polymer, and m-phenylenediamine compound FUJIFILM CORPORATION (JP) 2023-11-07 US disclosed
US-11806661-B2 Polymer and method for producing the same, gas separation membrane, gas separation module, and gas separation apparatus using the polymer, and m-phenylenediamine compound FUJIFILM CORPORATION (JP) 2023-11-07 US disclosed
US-20230119573-A1 GAS SEPARATION MEMBRANE, GAS SEPARATION MODULE, GAS SEPARATION APPARATUS, AND POLYIMIDE COMPOUND FUJIFILM CORPORATION (JP) 2023-04-20 US disclosed
US-20230106839-A1 LAMINATE, SINGLE-SIDED METAL-CLAD LAMINATED SHEET, AND MULTI-LAYER PRINTED WIRING BOARD KANEKA CORPORATION (JP) 2023-04-06 US disclosed
US-20230002562-A1 POLYSILOXANE COPOLYMER, METHOD FOR PREPARING THE SAME AND RESIN COMPOSITION INCLUDING THE SAME HUNETPLUS CO., LTD. (KR) 2023-01-05 US disclosed
CN-112940316-B Polyimide film and preparation method and application thereof 上海八亿时空先进材料有限公司 2022-07-29 CN disclosed
CN-113563585-B Polyimide and application thereof in metal laminated plate 上海八亿时空先进材料有限公司 2022-06-17 CN disclosed
WO-2021256237-A1 GAS SEPARATION MEMBRANE, GAS SEPARATION MODULE, GAS SEPARATION APPARATUS, AND POLYIMIDE COMPOUND 富士フイルム株式会社 2021-12-23 WO disclosed
US-7193020-B2 Film and laminate of the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-03-20 US disclosed
US-7115681-B2 polyimide resin and a thermosetting resin; can be bonded and cured at a comparatively low temperature, is soluble in a solvent and has excellent heat resistance and adhesion KANEKA CORPORATION (JP) 2006-10-03 US disclosed
US-20060115670-A1 Thermoplastic polyimide resin film, multilayer body and method for manufacturing printed wiring board composed of same KANEKA CORPORATION (JP) 2006-06-01 US disclosed
US-6810181-B2 LAYER OF A FLUORINE-CONTAINING POLYIMIDE AND A LAYER OF A FLUORINE-FREE RESIN IS INTERPOSED BETWEEN THE POLYIMIDE LAYER AND THE ELECTRODE HITACHI CHEMICAL CO., LTD. (JP) 2004-10-26 US disclosed
US-20040176526-A1 Resin composition KANEKA CORPORAITON (JP) 2004-09-09 US disclosed
US-20040096161-A1 Electrode structure HITACHI CHEMICAL CO., LTD. (JP) 2004-05-20 US disclosed
US-20030194573-A1 Multilayer structure and multilayer wiring board using the same KANEKA CORPORATION (JP) 2003-10-16 US disclosed
EP-0247731-B1 NOVEL PARA- OR META-TERPHENYLTETRACARBOXYLIC ACID, DIANHYDRIDE THEREOF AND PROCESS FOR PREPARING THE SAME Hitachi Chemical Co., Ltd. (JP) 1991-08-21 EP disclosed
US-4912233-A Para- or meta-terphenyltetracarboxylic acid, dianhydride thereof and process for preparing the same HITACHI CHEMICAL COMPANY, LTD. (JP) 1990-03-27 US disclosed
EP-0247731-A1 Novel para- or meta-terphenyltetracarboxylic acid, dianhydride thereof and process for preparing the same Hitachi Chemical Co., Ltd. (JP) 1987-12-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11806661-B2 Polymer and method for producing the same, gas separation membrane, gas separation module, and gas separation apparatus using the polymer, and m-phenylenediamine compound PRMT9, PRMT1, PNMT ALOX15 4463/4885TDP1 2677/4885ALDH1A1 2452/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.