Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | GLS | O94925 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28814233 | 1.00 | ALDH1A1 (0.41) | ALDH1A1CA12CA9ELANECASP3 | |
| SCHEMBL10496308 | 0.79 | CASP3 (0.41) | ALDH1A1CA12CA9ELANECASP3 | |
| SCHEMBL9944717 | 0.78 | CASP3 (0.43) | ALDH1A1CA12CA9CASP3MEN1 | |
| SCHEMBL4368833 | 0.75 | ALDH1A1 (0.44) | ALDH1A1CA12CA9ELANECASP3 | |
| SCHEMBL3275912 | 0.74 | CASP3 (0.43) | ALDH1A1ELANECASP3MEN1NPC1 | |
| SCHEMBL30472938 | 0.73 | CASP3 (0.46) | ALDH1A1CASP3MEN1NPC1RAB9A | |
| SCHEMBL2156119 | 0.73 | CASP3 (0.46) | ALDH1A1CASP3MEN1NPC1RAB9A | |
| SCHEMBL5706512 | 0.73 | KMT2A (0.44) | ALDH1A1CA12CA9ELANECASP3 | |
| SCHEMBL14499007 | 0.73 | ALDH1A1 (0.43) | ALDH1A1CA12CA9ELANECASP3 | |
| SCHEMBL534520 | 0.73 | ALDH1A1 (0.43) | ALDH1A1CA12CA9ELANECASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105777732-B | A kind of synthetic method and its application of Rivaroxaban intermediate | 深圳翰宇药业股份有限公司 | 2019-03-19 | — | — | CN | disclosed |
| CN-105777732-B | A kind of synthetic method and its application of Rivaroxaban intermediate | 深圳翰宇药业股份有限公司 | 2019-03-19 | — | — | CN | disclosed |
| CN-105777732-A | Method for synthesizing Rivaroxaban intermediate and application of method | 深圳翰宇药业股份有限公司 | 2016-07-20 | — | — | CN | disclosed |
| CN-105777732-A | Method for synthesizing Rivaroxaban intermediate and application of method | 深圳翰宇药业股份有限公司 | 2016-07-20 | — | — | CN | disclosed |