Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TGM2 | P21980 | 1/20 | 0.38 |
| ▸ | GLS | O94925 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.38 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9944717 | 0.83 | CASP3 (0.43) | ALDH1A1CA12CA9CASP3MEN1 | |
| SCHEMBL10496308 | 0.79 | CASP3 (0.41) | ALDH1A1CA12CA9CASP3MEN1 | |
| SCHEMBL30472938 | 0.78 | CASP3 (0.46) | ALDH1A1CASP3MEN1NPC1RAB9A | |
| SCHEMBL2156119 | 0.78 | CASP3 (0.46) | ALDH1A1CASP3MEN1NPC1RAB9A | |
| SCHEMBL7286383 | 0.75 | CASP3 (0.41) | ALDH1A1CA12CA9CASP3TGM2 | |
| SCHEMBL5706500 | 0.75 | CA12 (0.47) | ALDH1A1CA12CA9CASP3MEN1 | |
| SCHEMBL28814233 | 0.75 | ALDH1A1 (0.41) | ALDH1A1CA12CA9CASP3MEN1 | |
| SCHEMBL28078141 | 0.75 | ALDH1A1 (0.41) | ALDH1A1CA12CA9CASP3MEN1 | |
| SCHEMBL19067757 | 0.74 | CASP3 (0.43) | ALDH1A1CA12CA9CASP3MEN1 | |
| SCHEMBL28110900 | 0.74 | CASP3 (0.43) | ALDH1A1CASP3MEN1KMT2ACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2114158-A1 | 3-SUBSTITUTED-[1,2,3]BENZOTRIAZINONE COMPOUNDS FOR ENHANCING GLUTAMATERGIC SYNAPTIC RESPONSES | CORTEX PHARMACEUTICALS, INC. (US) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008085505-A1 | 3-SUBSTITUTED-[1,2,3]BENZOTRIAZINONE COMPOUNDS FOR ENHANCING GLUTAMATERGIC SYNAPTIC RESPONSES | CORTEX PHARMACEUTICALS, INC. (US) | 2008-07-17 | — | — | WO | disclosed |