Tert-Butylbenzene

Tert-Butylbenzene

SCHEMBL28078162

CC(C)(C)c1ccccc1.CN1CCNCC1

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR3A P46098 2/20 0.47
HTR1A P08908 1/20 0.47
HPGD P15428 2/20 0.46
CHRM2 P08172 2/20 0.45
CHRM4 P08173 2/20 0.45
CHRM5 P08912 2/20 0.45
CHRM1 P11229 2/20 0.45
CHRM3 P20309 2/20 0.45
SIGMAR1 Q99720 4/20 0.44
ADRB1 P08588 2/20 0.44
HTR3E A5X5Y0 1/20 0.44
HTR3B O95264 1/20 0.44
HTR3D Q70Z44 1/20 0.44
HTR3C Q8WXA8 1/20 0.44
OPRD1 P41143 1/20 0.43
ALDH1A1 P00352 2/20 0.41
HTT P42858 1/20 0.41
ALOX15 P16050 1/20 0.41
MEN1 O00255 4/20 0.41
KMT2A Q03164 4/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL10725648 0.79 HTR1A (0.53) HTR3AHTR1ASIGMAR1ADRB1HTR3E
Methylpiperazine SCHEMBL28182481 0.78 ADRB1 (0.44) HTR3AHTR1ACHRM2CHRM4CHRM5
Methylpiperazine SCHEMBL27759929 0.78 ADRB1 (0.50) HTR3AHTR1ASIGMAR1ADRB1HTR3E
Methylpiperazine SCHEMBL11764299 0.76 CYP1A2 (0.59) CHRM2CHRM4CHRM5CHRM1CHRM3
Methylpiperazine SCHEMBL27594948 0.76 SIGMAR1 (0.47) HTR3AHTR1ASIGMAR1ADRB1HTR3E
Tert-Butylbenzene SCHEMBL31609573 0.76 MAPK1 (0.52) ALDH1A1ALOX15KMT2AMAPTLMNA
O-Xylene SCHEMBL28078166 0.75 ADRB1 (0.59) HTR3AHTR1ASIGMAR1ADRB1HTR3E
SCHEMBL2697321 0.74 CYP2B6 (0.66) HTR3AHTR1ACHRM2CHRM4CHRM5
SCHEMBL9202300 0.74 CHRM2 (0.46) HTR3AHTR1ACHRM2CHRM4CHRM5
Methylpiperazine SCHEMBL27973874 0.74 SIGMAR1 (0.45) HTR3AHTR1ACHRM2CHRM4CHRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104046246-B The chemical-mechanical planarization of tungsten-containing substrate 气体产品与化学公司 2016-06-15 CN claimed
CN-104046246-B The chemical-mechanical planarization of tungsten-containing substrate 气体产品与化学公司 2016-06-15 CN disclosed