Methacrylic Acid

Methacrylic Acid

SCHEMBL28098650

C=C(C)C(=O)O.C=C(CCCC)C(=O)OCO

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.43
CES1 P23141 2/20 0.35
CES2 O00748 1/20 0.34
ALDH1A1 P00352 3/20 0.34
THRB P10828 2/20 0.33
FNTA P49354 1/20 0.33
FNTB P49356 1/20 0.33
PGGT1B P53609 1/20 0.33
PRKCA P17252 2/20 0.33
PAM P19021 2/20 0.33
AKR1B1 P15121 1/20 0.32
TP53 P04637 1/20 0.32
MAPT P10636 1/20 0.32
MAPK1 P28482 1/20 0.32
DGKA P23743 1/20 0.32
GPR84 Q9NQS5 2/20 0.31
PPARG P37231 2/20 0.31
PPARD Q03181 2/20 0.31
PPARA Q07869 2/20 0.31
SLC22A6 Q4U2R8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3151795 0.91 TSHR (0.41) TSHRCES1CES2ALDH1A1PRKCA
Methacrylic Acid SCHEMBL28300425 0.88 TSHR (0.44) TSHRCES1CES2ALDH1A1THRB
Methacrylic Acid SCHEMBL28078237 0.88 TSHR (0.44) TSHRCES1CES2ALDH1A1THRB
Methacrylic Acid SCHEMBL27706309 0.86 TSHR (0.56) TSHRCES1CES2ALDH1A1THRB
SCHEMBL25251289 0.84 TSHR (0.47) TSHRCES1CES2ALDH1A1PRKCA
Methacrylic Acid SCHEMBL27869564 0.82 ALDH1A1 (0.45) TSHRCES1CES2ALDH1A1THRB
Methacrylic Acid SCHEMBL11252010 0.81 TSHR (0.50) TSHRALDH1A1THRBFNTAFNTB
Methacrylic Acid SCHEMBL29254386 0.80 TSHR (0.67) TSHRALDH1A1THRBFNTAFNTB
Methacrylic Acid SCHEMBL11267068 0.80 TSHR (0.62) TSHRALDH1A1THRBFNTAFNTB
Methacrylic Acid SCHEMBL11249801 0.80 TSHR (0.67) TSHRALDH1A1THRBFNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105936810-A Optical film with adhesive layer 琳得科株式会社 2016-09-14 CN disclosed