Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.51 |
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | HTR2B | P41595 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16398273 | 1.00 | HTR2C (0.51) | HTR2CHTR2AHTR2BKDM4EMEN1 | |
| SCHEMBL28248304 | 0.84 | HTR2C (0.56) | HTR2CHTR2AHTR2BKDM4EMEN1 | |
| Propylamine SCHEMBL11093527 | 0.82 | HTR2C (0.46) | HTR2CHTR2AHTR2BKDM4EMEN1 | |
| SCHEMBL16397928 | 0.79 | ALOX15 (0.45) | HTR2CKDM4EMEN1NPC1GAA | |
| SCHEMBL16397926 | 0.79 | ALOX15 (0.45) | HTR2CKDM4EMEN1NPC1GAA | |
| SCHEMBL8329714 | 0.77 | HTR2C (0.54) | HTR2CHTR2AHTR2BKDM4EMEN1 | |
| SCHEMBL31258231 | 0.76 | HTR2C (0.48) | HTR2CHTR2AHTR2BKDM4EMEN1 | |
| SCHEMBL28084687 | 0.75 | HTR2C (0.46) | HTR2CHTR2AHTR2BKDM4EMEN1 | |
| SCHEMBL10773544 | 0.75 | DRD2 (0.50) | HTR2CHTR2AHTR2BDRD2DDB1 | |
| SCHEMBL1515134 | 0.74 | HTR2C (0.77) | HTR2CHTR2AHTR2BDRD2DDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105658656-A | 1, 1' -spiroindane-7, 7-bisphosphine oxides as highly active supporting ligands in palladium-catalyzed asymmetric Heck reactions | 南洋理工大学 | 2016-06-08 | — | — | CN | disclosed |