Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 4/20 | 0.58 |
| ▸ | HSD17B3 | P37058 | 5/20 | 0.54 |
| ▸ | TTR | P02766 | 2/20 | 0.53 |
| ▸ | EYA3 | Q99504 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL719026 | 0.78 | EYA3 (0.48) | SLC22A12TTREYA3ALDH1A1KDM4E | |
| SCHEMBL14176730 | 0.78 | KDM4E (0.57) | HSD17B3ALDH1A1KDM4ELMNAHSD17B10 | |
| SCHEMBL1287413 | 0.74 | SLC22A12 (1.00) | SLC22A12HSD17B3TTREYA3ALDH1A1 | |
| SCHEMBL28448917 | 0.73 | MEN1 (0.52) | SLC22A12EYA3ALDH1A1KDM4ELMNA | |
| SCHEMBL5240867 | 0.73 | SLC22A12 (0.68) | SLC22A12HSD17B3TTREYA3ALDH1A1 | |
| SCHEMBL28002580 | 0.72 | KDM4E (0.62) | HSD17B3ALDH1A1KDM4ELMNAHSD17B10 | |
| SCHEMBL5242021 | 0.72 | SLC22A12 (0.67) | SLC22A12HSD17B3TTREYA3ALDH1A1 | |
| SCHEMBL28383872 | 0.71 | HSD17B3 (0.73) | HSD17B3ALDH1A1KDM4ELMNAHSD17B10 | |
| SCHEMBL14396891 | 0.71 | ESR1 (0.55) | HSD17B3ALDH1A1KDM4ELMNAHSD17B10 | |
| SCHEMBL3762732 | 0.70 | HSD17B3 (1.00) | HSD17B3ALDH1A1KDM4ELMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105646414-A | Synthetic method of 6-hydroxyl-2-methylbenzofuran type compound | 和记黄埔医药（苏州）有限公司 | 2016-06-08 | — | — | CN | disclosed |