Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | NQO1 | P15559 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | GABRP | O00591 | 2/20 | 0.39 |
| ▸ | GABRD | O14764 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.39 |
| ▸ | GABRE | P78334 | 2/20 | 0.39 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.39 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL719026 | 0.77 | EYA3 (0.48) | MEN1LMNAKMT2APTPN1SLC22A12 | |
| SCHEMBL30136586 | 0.75 | KMT2A (0.46) | MEN1LMNAKMT2APTPN1NQO1 | |
| SCHEMBL27992814 | 0.75 | KMT2A (0.46) | MEN1LMNAKMT2APTPN1NQO1 | |
| SCHEMBL20561973 | 0.74 | ERN1 (0.33) | MEN1LMNAKMT2A | |
| SCHEMBL28078332 | 0.73 | SLC22A12 (0.58) | LMNAKMT2ASLC22A12EYA3KDM4E | |
| SCHEMBL22612472 | 0.72 | CYP2C9 (0.40) | MEN1LMNAKMT2ASLC22A12EYA3 | |
| SCHEMBL8910 | 0.71 | TNKS (0.52) | MEN1LMNAKMT2APTPN1GABRP | |
| SCHEMBL24756657 | 0.70 | NQO1 (0.44) | MEN1LMNAKMT2ANQO1RAB9A | |
| SCHEMBL8856 | 0.70 | GABRA1 (0.53) | MEN1LMNAKMT2ANQO1RAB9A | |
| SCHEMBL24757778 | 0.69 | MEN1 (0.49) | MEN1LMNAKMT2APTPN1NQO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117586272-A | Heterocyclic compound, preparation method and application thereof in medicine | 苏州信诺维医药科技股份有限公司 | 2024-02-23 | — | — | CN | claimed |
| CN-112979661-A | Heterocyclic compound, preparation method and application thereof in medicine | 苏州信诺维医药科技有限公司 | 2021-06-18 | — | — | CN | claimed |
| CN-111615515-A | Heterocyclic compound, preparation method and application thereof in medicine | 苏州信诺维医药科技有限公司 | 2020-09-01 | — | — | CN | claimed |
| CN-117586272-A | Heterocyclic compound, preparation method and application thereof in medicine | 苏州信诺维医药科技股份有限公司 | 2024-02-23 | — | — | CN | disclosed |
| CN-111615515-B | Heterocyclic compound, preparation method and application thereof in medicine | 苏州信诺维医药科技股份有限公司 | 2023-11-24 | — | — | CN | disclosed |
| CN-112979661-B | Heterocyclic compound, preparation method and application thereof in medicine | 苏州信诺维医药科技股份有限公司 | 2022-05-17 | — | — | CN | disclosed |
| CN-112979661-A | Heterocyclic compound, preparation method and application thereof in medicine | 苏州信诺维医药科技有限公司 | 2021-06-18 | — | — | CN | disclosed |
| CN-111615515-A | Heterocyclic compound, preparation method and application thereof in medicine | 苏州信诺维医药科技有限公司 | 2020-09-01 | — | — | CN | disclosed |