Pyrazine

Pyrazine

SCHEMBL28078427

c1c[nH]cn1.c1c[nH]cn1.c1cnccn1

nearest known ligand 0.87

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.87
FKBP5 Q13451 1/20 0.87

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyrazine SCHEMBL1671928 1.00 ALDH1A1 (0.87) ALDH1A1FKBP5
Imidazole SCHEMBL28744226 0.93 ALDH1A1 (1.00) ALDH1A1FKBP5
Imidazole SCHEMBL1331920 0.93
Imidazole SCHEMBL19028065 0.93 ALDH1A1 (1.00) ALDH1A1FKBP5
Imidazole SCHEMBL2684565 0.93 ALDH1A1 (1.00) ALDH1A1FKBP5
Imidazole SCHEMBL30382963 0.93
Imidazole SCHEMBL1331382 0.93
Imidazole SCHEMBL897 0.93
Imidazole SCHEMBL2635292 0.93
Pyrazine SCHEMBL8970869 0.91 ALDH1A1 (0.72) ALDH1A1FKBP5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105646500-A Diimidazo-pyrazine derivative and application thereof 中节能万润股份有限公司 2016-06-08 CN claimed
CN-111848624-A Benzodiimidazole compound, hole injection material, OLED device and preparation method and application thereof 上海和辉光电有限公司 2020-10-30 CN disclosed
CN-105646500-A Diimidazo-pyrazine derivative and application thereof 中节能万润股份有限公司 2016-06-08 CN disclosed