Pyrazine

Pyrazine

SCHEMBL8970869

C#N.c1c[nH]cn1.c1cnccn1

nearest known ligand 0.72

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Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.72
FKBP5 Q13451 1/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Imidazole SCHEMBL28084098 0.94
Imidazole SCHEMBL28180897 0.92 ALDH1A1 (0.77) ALDH1A1FKBP5
Pyrazine SCHEMBL28078427 0.91 ALDH1A1 (0.87) ALDH1A1FKBP5
Pyrazine SCHEMBL1671928 0.91 ALDH1A1 (0.87) ALDH1A1FKBP5
Imidazole SCHEMBL1815089 0.85
Imidazole SCHEMBL29178177 0.85
Imidazole SCHEMBL2363813 0.85
Imidazole SCHEMBL1331920 0.85
Imidazole SCHEMBL1331382 0.85
Imidazole SCHEMBL2684565 0.85 ALDH1A1 (1.00) ALDH1A1FKBP5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0584815-B1 High tabularity high chloride emulsions of exceptional stability EASTMAN KODAK CO (US) 1996-03-06 EP disclosed
EP-0584815-A1 High tabularity high chloride emulsions of exceptional stability EASTMAN KODAK COMPANY (US) 1994-03-02 EP disclosed
US-5275930-A Chemically sensitized silver halide epitaxial deposits EASTMAN KODAK COMPANY (US) 1994-01-04 US disclosed