Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.46 |
| ▸ | XDH | P47989 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28230672 | 0.87 | NOTUM (0.48) | LMNAHTTMAPTCA1CA2 | |
| SCHEMBL31733918 | 0.83 | RAB9A (0.49) | LMNAHTTMAPK1RAB9AMAPT | |
| SCHEMBL30485947 | 0.83 | CA12 (0.50) | LMNAHTTMAPK1RAB9AMAPT | |
| SCHEMBL1988161 | 0.83 | HTT (0.71) | LMNAHTTMAPK1RAB9AMAPT | |
| SCHEMBL29690359 | 0.82 | MGLL (0.49) | LMNAHTTRAB9AMAPTCA1 | |
| SCHEMBL1899655 | 0.82 | MGLL (0.49) | LMNAHTTRAB9AMAPTCA1 | |
| SCHEMBL30929945 | 0.81 | RAB9A (0.64) | LMNAHTTMAPK1RAB9AMAPT | |
| SCHEMBL27840247 | 0.81 | USP2 (0.61) | LMNAHTTMAPK1RAB9AMAPT | |
| SCHEMBL27898472 | 0.81 | KMT2A (0.52) | RAB9AMAPTCA1CA2CA12 | |
| SCHEMBL8111959 | 0.80 | LMNA (0.53) | LMNAHTTMAPK1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105873916-B | Amide derivatives for GPR119 agonists | 株式会社钟根堂 | 2019-08-27 | — | — | CN | disclosed |
| CN-110028494-A | Amide derivatives, its stereoisomer or its pharmaceutically acceptable salt and the pharmaceutical composition comprising it | 株式会社钟根堂 | 2019-07-19 | — | — | CN | disclosed |
| CN-106061977-B | 1, 2-dihydro-3H-pyrrolo [1,2-C ] imidazol-3-one derivatives and their use as antibacterial agents | 爱杜西亚药品有限公司 | 2018-10-26 | — | — | CN | disclosed |
| CN-104364246-B | Piperidine derivatives useful as GPR119 agonists | 株式会社钟根堂 | 2018-05-22 | — | — | CN | disclosed |
| CN-105143193-B | Biaryl or heterocyclic biaryl substituted cyclohexene derivative compounds as CETP inhibitors | 株式会社钟根堂 | 2017-12-15 | — | — | CN | disclosed |
| CN-106061977-A | 1, 2-dihydro-3H-pyrrolo [1,2-C ] imidazol-3-one derivatives and their use as antibacterial agents | 埃科特莱茵药品有限公司 | 2016-10-26 | — | — | CN | disclosed |
| CN-103339141-B | C-28 amines of C-3 modified betulinic acid derivatives as HIV maturation inhibitors | 百时美施贵宝公司 | 2016-08-24 | — | — | CN | disclosed |
| CN-105873916-A | Amide derivatives for GPR119 agonists | 株式会社钟根堂 | 2016-08-17 | — | — | CN | disclosed |