3,3-Diphenylpropanoic Acid

3,3-Diphenylpropanoic Acid

SCHEMBL28079188

O=C(O)CC(c1ccccc1)c1ccccc1.[LiH]

nearest known ligand 0.57

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABBR2 O75899 1/20 0.57
GABBR1 Q9UBS5 1/20 0.57
FFAR1 O14842 1/20 0.53
CPA1 P15085 2/20 0.52
CPB1 P15086 1/20 0.52
CPA3 P15088 1/20 0.52
CPB2 Q96IY4 1/20 0.52
CYP2C19 P33261 2/20 0.52
LMNA P02545 3/20 0.50
POLB P06746 1/20 0.50
CYP2D6 P10635 1/20 0.48
SRC P12931 1/20 0.48
MAPK1 P28482 1/20 0.46
CACNA1H O95180 1/20 0.46
CACNA2D1 P54289 1/20 0.46
CACNA1B Q00975 1/20 0.46
CACNB1 Q02641 1/20 0.46
CACNA1C Q13936 1/20 0.46
HPGD P15428 1/20 0.46
MAPT P10636 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
3,3-Diphenylpropanoic Acid SCHEMBL66473 0.97 GABBR2 (0.59) GABBR2GABBR1FFAR1CPA1CPB1
3,3-Diphenylpropanoic Acid SCHEMBL5283373 0.97 GABBR2 (0.59) GABBR2GABBR1FFAR1CPA1CPB1
3,3-Diphenylpropanoic Acid SCHEMBL5740483 0.95 GABBR2 (0.57) GABBR2GABBR1FFAR1CPA1CPB1
3,3-Diphenylpropanoic Acid SCHEMBL28079326 0.95 GABBR2 (0.57) GABBR2GABBR1FFAR1CPA1CPB1
3,3-Diphenylpropanoic Acid SCHEMBL9100138 0.95 GABBR2 (0.57) GABBR2GABBR1FFAR1CPA1CPB1
SCHEMBL3658988 0.87 CNR1 (0.51) GABBR2GABBR1FFAR1CPA1CPB1
3,3-Diphenylpropanoic Acid SCHEMBL20981393 0.87 FFAR1 (0.59) GABBR2GABBR1FFAR1CPA1CPB1
SCHEMBL5499422 0.87 FFAR1 (0.59) GABBR2GABBR1FFAR1LMNA
SCHEMBL9155517 0.85 CACNA2D1 (0.55) GABBR2GABBR1FFAR1CYP2C19LMNA
SCHEMBL170301 0.85 SLC6A2 (0.55) GABBR2GABBR1FFAR1CYP2C19LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105801404-A S-2-hydroxy-3-methoxy-3, 3-dibenzylpropionic acid and preparation method thereof 辽宁诺康生物制药有限责任公司 2016-07-27 CN disclosed