Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 3/20 | 0.58 |
| ▸ | GABBR1 | Q9UBS5 | 3/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | DRD3 | P35462 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | CACNA2D1 | P54289 | 4/20 | 0.55 |
| ▸ | CACNB1 | Q02641 | 4/20 | 0.55 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15614165 | 1.00 | GABBR2 (0.58) | GABBR2GABBR1CYP2C9LMNACYP2D6 | |
| SCHEMBL3520190 | 0.94 | GABBR2 (0.63) | GABBR2GABBR1CYP2C9LMNACYP2D6 | |
| Hydrochloric Acid SCHEMBL11527826 | 0.92 | GABBR2 (0.61) | GABBR2GABBR1CYP2C9LMNACYP2D6 | |
| 3,3-Diphenylpropanoic Acid SCHEMBL66473 | 0.87 | GABBR2 (0.59) | GABBR2GABBR1LMNACYP2D6CYP2C19 | |
| 3,3-Diphenylpropanoic Acid SCHEMBL5283373 | 0.87 | GABBR2 (0.59) | GABBR2GABBR1LMNACYP2D6CYP2C19 | |
| 3,3-Diphenylpropanoic Acid SCHEMBL28079326 | 0.85 | GABBR2 (0.57) | GABBR2GABBR1LMNACYP2D6CYP2C19 | |
| 3,3-Diphenylpropanoic Acid SCHEMBL9100138 | 0.85 | GABBR2 (0.57) | GABBR2GABBR1LMNACYP2D6CYP2C19 | |
| 3,3-Diphenylpropanoic Acid SCHEMBL5740483 | 0.85 | GABBR2 (0.57) | GABBR2GABBR1LMNACYP2D6CYP2C19 | |
| 3,3-Diphenylpropanoic Acid SCHEMBL28079188 | 0.85 | GABBR2 (0.57) | GABBR2GABBR1LMNACYP2D6CYP2C19 | |
| SCHEMBL18228863 | 0.85 | TACR1 (0.58) | GABBR2GABBR1MEN1KMT2ACACNA2D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3262026-B1 | NEW TRIFLUOROMETHYLPROPANAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2020-03-18 | — | — | EP | disclosed |
| US-9980929-B2 | Trifluoromethylpropanamide derivatives | HOFFMAN-LA ROCHE INC. (US) | 2018-05-29 | — | — | US | disclosed |
| US-20170348257-A1 | NEW TRIFLUOROMETHYLPROPANAMIDE DERIVATIVES | HOFFMANN-LA ROCHE INC. (US) | 2017-12-07 | — | — | US | disclosed |
| US-20060166984-A1 | Amino substituted benzo(hetero)cyclic derivatives | BASF AKTIENGESELLSCHAFT (DE) | 2006-07-27 | — | — | US | disclosed |
| EP-1603395-A2 | AMINO SUBSTITUTED BENZO(HETERO)CYCLIC DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 2005-12-14 | — | — | EP | disclosed |
| WO-2004080170-A2 | AMINO SUBSTITUTED BENZO(HETERO)CYCLIC DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 2004-09-23 | — | — | WO | disclosed |
| CN-1024488-C | Benzhydryl compounds as henbicide antidotes | MONSANTO CO (US) | 1994-05-18 | — | — | CN | disclosed |
| CN-87102879-A | Benzhydryl compounds as herbicide antidotes | — | 1987-10-28 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170348257-A1 | NEW TRIFLUOROMETHYLPROPANAMIDE DERIVATIVES | PRMT7, GFRA3, PRMT5 | GABBR2 349/4885GABBR1 582/4885CYP2C9 430/4885 |
| US-20060166984-A1 | Amino substituted benzo(hetero)cyclic derivatives | CBR3, L3MBTL3, BRS3 | GABBR2 1010/4885GABBR1 1025/4885CYP2C9 3006/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.