Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 5/20 | 0.59 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.55 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.51 |
| ▸ | MMP12 | P39900 | 1/20 | 0.51 |
| ▸ | MMP13 | P45452 | 1/20 | 0.51 |
| ▸ | MMP14 | P50281 | 1/20 | 0.51 |
| ▸ | ACP3 | P15309 | 2/20 | 0.50 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.50 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.50 |
| ▸ | CTSA | P10619 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 3,3-Diphenylpropanoic Acid SCHEMBL5283373 | 0.89 | GABBR2 (0.59) | FFAR1LMNAGABBR2GABBR1 | |
| 3,3-Diphenylpropanoic Acid SCHEMBL66473 | 0.89 | GABBR2 (0.59) | FFAR1LMNAGABBR2GABBR1 | |
| 3,3-Diphenylpropanoic Acid SCHEMBL28079188 | 0.87 | GABBR2 (0.57) | FFAR1LMNAGABBR2GABBR1 | |
| 3,3-Diphenylpropanoic Acid SCHEMBL5740483 | 0.87 | GABBR2 (0.57) | FFAR1LMNAGABBR2GABBR1 | |
| 3,3-Diphenylpropanoic Acid SCHEMBL28079326 | 0.87 | GABBR2 (0.57) | FFAR1LMNAGABBR2GABBR1 | |
| 3,3-Diphenylpropanoic Acid SCHEMBL9100138 | 0.87 | GABBR2 (0.57) | FFAR1LMNAGABBR2GABBR1 | |
| SCHEMBL29031805 | 0.84 | CYP2C19 (0.57) | FFAR1CHRNB2CHRNA4PTGS2ACP3 | |
| SCHEMBL659200 | 0.83 | GABBR2 (0.60) | FFAR1PTGS2MMP2MMP9MMP12 | |
| SCHEMBL3658988 | 0.83 | CNR1 (0.51) | FFAR1LMNAGAAGABBR2GABBR1 | |
| SCHEMBL6002264 | 0.82 | GABBR2 (0.58) | FFAR1LMNATSHRHTTGABBR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1066259-B1 | BIOCIDAL BENZYLBIPHENYL DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2007-01-10 | — | — | EP | disclosed |
| US-6440440-B1 | BACTERICIDES, FUNGICIDES, NEMATOCIDES, MITICIDES, INSECTICIDES, AND HERBICIDES | JANSSEN PHARMACEUTICA N.V. (BE) | 2002-08-27 | — | — | US | disclosed |
| EP-1066259-A1 | BIOCIDAL BENZYLBIPHENYL DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 2001-01-10 | — | — | EP | disclosed |
| WO-1999051578-A1 | BIOCIDAL BENZYLBIPHENYL DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1999-10-14 | — | — | WO | disclosed |