SCHEMBL28079252

SCHEMBL28079252

O=COCc1cc([N+](=O)[O-])n[nH]1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 1/20 0.32
KCNJ1 P48048 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL173914 0.74 HCAR2 (0.47) HCAR2
SCHEMBL14714005 0.74 MEN1 (0.30)
SCHEMBL12200985 0.74 HCAR2 (0.46) HCAR2
SCHEMBL28079412 0.73 HCAR2 (0.35) HCAR2
SCHEMBL31319635 0.71 HCAR2 (0.49) HCAR2
SCHEMBL16622728 0.71 LMNA (0.35)
SCHEMBL28262261 0.71
SCHEMBL28038521 0.71 HPGD (0.33)
SCHEMBL27683382 0.70 CYP1A2 (0.38) HCAR2
Butyl Formate SCHEMBL28320805 0.70 NPC1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105658640-A Alkynyl alcohols and methods of use 豪夫迈·罗氏有限公司 2016-06-08 CN disclosed