Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC34A1 | Q06495 | 14/20 | 0.42 |
| ▸ | LCK | P06239 | 2/20 | 0.35 |
| ▸ | RORC | P51449 | 2/20 | 0.34 |
| ▸ | INSR | P06213 | 1/20 | 0.31 |
| ▸ | LYN | P07948 | 1/20 | 0.31 |
| ▸ | HCK | P08631 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20074787 | 0.76 | SLC34A1 (0.54) | SLC34A1LCK | |
| SCHEMBL16517332 | 0.74 | RORC (0.51) | SLC34A1RORCMAPT | |
| SCHEMBL16517539 | 0.73 | SCN9A (0.49) | RORC | |
| SCHEMBL28079257 | 0.69 | MPO (0.43) | RORC | |
| SCHEMBL3846775 | 0.64 | HSP90AA1 (0.49) | MAPT | |
| SCHEMBL20074751 | 0.63 | SLC34A1 (0.50) | SLC34A1LCK | |
| SCHEMBL20074851 | 0.62 | SLC34A1 (0.51) | SLC34A1 | |
| SCHEMBL21177924 | 0.61 | NPSR1 (0.48) | SLC34A1MAPT | |
| SCHEMBL24740066 | 0.61 | KMT2A (0.44) | — | |
| SCHEMBL28051978 | 0.61 | EGFR (0.56) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105658640-A | Alkynyl alcohols and methods of use | 豪夫迈·罗氏有限公司 | 2016-06-08 | — | — | CN | disclosed |