Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 3/20 | 0.52 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.52 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.52 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.52 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.52 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | FBP1 | P09467 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL195598 | 0.79 | P2RY12 (0.53) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL682128 | 0.78 | MAPT (0.63) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL1548554 | 0.78 | FBP1 (0.43) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL4098072 | 0.77 | FBP1 (0.43) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL5625377 | 0.77 | KMT2A (0.53) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL22089492 | 0.77 | STS (0.57) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL4100013 | 0.77 | STS (0.69) | MAPTKMT2AP2RY12 | |
| SCHEMBL194745 | 0.76 | MAPT (0.53) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL22115151 | 0.75 | STS (0.47) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL5960002 | 0.75 | MAPT (0.53) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105130855-B | Succinylated hydroxy amine derivatives and application thereof | 约翰斯霍普金斯大学 | 2018-05-25 | — | — | CN | disclosed |
| CN-105919987-A | N-acyloxysulfonamide And N-hydroxy-n-acylsulfonamide Derivatives And Use Thereof | 约翰斯霍普金斯大学 | 2016-09-07 | — | — | CN | disclosed |
| CN-102753520-B | N-acyloxysulfonamide and N-hydroxy-N-acylsulfonamide derivatives | 约翰斯霍普金斯大学 | 2016-06-08 | — | — | CN | disclosed |