Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | LMNA | P02545 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 7/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.47 |
| ▸ | HTT | P42858 | 5/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1548554 | 0.89 | FBP1 (0.43) | MAPTLMNAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL5960001 | 0.80 | NPC1 (0.38) | MAPTLMNAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL7578134 | 0.77 | LMNA (0.71) | MAPTLMNAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL28079459 | 0.75 | PSEN1 (0.52) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7573143 | 0.75 | ALDH1A1 (0.64) | MAPTLMNAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL15914448 | 0.74 | KMT2A (0.47) | MAPTSMN1; SMN2KMT2AHTTNPC1 | |
| SCHEMBL5960273 | 0.73 | ALDH1A1 (0.62) | MAPTLMNAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL5731619 | 0.72 | POLB (0.54) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8297312 | 0.70 | SMN1; SMN2 (0.63) | MAPTLMNAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL29346029 | 0.69 | CA12 (0.46) | ALDH1A1SMN1; SMN2MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1412364-B1 | PLATELET ADP RECEPTOR INHIBITORS | PORTOLA PHARM INC (US) | 2006-09-13 | — | — | EP | disclosed |