Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.65 |
| ▸ | CA1 | P00915 | 10/20 | 0.64 |
| ▸ | CA2 | P00918 | 10/20 | 0.64 |
| ▸ | CA12 | O43570 | 9/20 | 0.64 |
| ▸ | CA9 | Q16790 | 9/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | CA6 | P23280 | 2/20 | 0.55 |
| ▸ | CA5A | P35218 | 2/20 | 0.55 |
| ▸ | CA7 | P43166 | 2/20 | 0.55 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.55 |
| ▸ | MMP1 | P03956 | 1/20 | 0.53 |
| ▸ | MMP2 | P08253 | 1/20 | 0.53 |
| ▸ | MMP9 | P14780 | 1/20 | 0.53 |
| ▸ | MMP8 | P22894 | 1/20 | 0.53 |
| ▸ | MMP13 | P45452 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30380602 | 0.95 | CYP2D6 (0.68) | CYP3A4CYP2D6CA1CA2CA12 | |
| SCHEMBL30380384 | 0.93 | CYP2D6 (0.66) | CYP3A4CYP2D6CA1CA2CA12 | |
| SCHEMBL2563975 | 0.89 | CYP3A4 (0.70) | CYP3A4CYP2D6CA1CA2CA12 | |
| SCHEMBL13591295 | 0.89 | CYP2D6 (0.60) | CYP3A4CYP2D6CA1CA2CA12 | |
| SCHEMBL11682917 | 0.83 | CYP2D6 (0.81) | CYP3A4CYP2D6CA1CA2CA12 | |
| SCHEMBL11520559 | 0.83 | CYP2D6 (0.81) | CYP3A4CYP2D6CA1CA2CA12 | |
| SCHEMBL4703731 | 0.82 | CA12 (0.71) | CA2CA12CA9ALDH1A1PKM | |
| SCHEMBL5435010 | 0.82 | GAA (0.60) | CA1CA2ALDH1A1PKMGAA | |
| SCHEMBL13357765 | 0.82 | CYP3A4 (0.66) | CYP3A4CYP2D6CA1CA2CA12 | |
| SCHEMBL4085333 | 0.82 | CA12 (0.80) | CYP3A4CYP2D6CA1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250136619-A1 | HETEROBIFUNCTIONAL COMPOUNDS AND THEIR USE IN TREATING DISEASE | HALDA THERAPEUTICS OPCO, INC. | 2025-05-01 | — | — | US | disclosed |
| WO-2023059581-A1 | HETEROBIFUNCTIONAL COMPOUNDS AND THEIR USE IN TREATING DISEASE | HALDA THERAPEUTICS OPCO, INC. (US) | 2023-04-13 | — | — | WO | disclosed |
| CN-105801582-A | Novel dihydro pteridinone derivative, preparing method thereof and application to medicine | 合肥工业大学 | 2016-07-27 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250136619-A1 | HETEROBIFUNCTIONAL COMPOUNDS AND THEIR USE IN TREATING DISEASE | CDK9, AURKB, AURKC | CYP3A4 3443/4885CYP2D6 3013/4885CA1 3810/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.