Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
| ▸ | CA9 | Q16790 | 11/20 | 0.64 |
| ▸ | CA1 | P00915 | 11/20 | 0.64 |
| ▸ | CA2 | P00918 | 11/20 | 0.64 |
| ▸ | CA12 | O43570 | 10/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.57 |
| ▸ | CA6 | P23280 | 2/20 | 0.55 |
| ▸ | CA5A | P35218 | 2/20 | 0.55 |
| ▸ | CA7 | P43166 | 2/20 | 0.55 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | PKM | P14618 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7092060 | 0.82 | ALDH1A1 (0.70) | CA9CA2CA12ALDH1A1MEN1 | |
| SCHEMBL4085333 | 0.82 | CA12 (0.80) | CYP3A4CA9CA1CA2CA12 | |
| SCHEMBL13357765 | 0.82 | CYP3A4 (0.66) | CYP3A4CA9CA1CA2CA12 | |
| SCHEMBL7532832 | 0.82 | TSHR (0.63) | CA1CA2ALDH1A1PKMMEN1 | |
| SCHEMBL28079518 | 0.82 | CYP3A4 (0.66) | CYP3A4CA9CA1CA2CA12 | |
| SCHEMBL14104604 | 0.81 | ALDH1A1 (0.75) | CA1CA2ALDH1A1PKMMEN1 | |
| SCHEMBL30380602 | 0.81 | CYP2D6 (0.68) | CYP3A4CA9CA1CA2CA12 | |
| SCHEMBL28736088 | 0.81 | CYP3A4 (0.69) | CYP3A4CA9CA1CA2CA12 | |
| SCHEMBL1082403 | 0.81 | CA12 (0.77) | CYP3A4CA9CA1CA2CA12 | |
| SCHEMBL14628032 | 0.79 | CYP3A4 (1.00) | CYP3A4CA9CA1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1433297-A | Topical compositions comprising protected functional thiols | PROCTER & GAMBLE (US) | 2003-07-30 | — | — | CN | disclosed |
| US-6544499-B1 | Polysiloxane or silicone resin, a linker, and a molecular hook for treating amino acid based substrates; hair care | THE PROCTER & GAMBLE COMPANY | 2003-04-08 | — | — | US | disclosed |
| US-6495125-B2 | MAY BE USED IN HAIR CARE, TEXTILE CARE, COSMETICS, ORAL CARE FORMULATIONS, SKIN, NAIL, LAUNDRY, ACNE CARE FORMULATIONS | THE PROCTER & GAMBLE COMPANY | 2002-12-17 | — | — | US | disclosed |
| US-20020012639-A1 | May be used in hair care, textile care, cosmetics, oral care formulations, skin, nail, laundry, acne care formulations | PROCTER & GAMBLE COMPANY, THE | 2002-01-31 | — | — | US | disclosed |
| EP-1143916-A2 | TOPICAL COMPOSITIONS COMPRISING PROTECTED FUNCTIONAL THIOLS | THE PROCTER & GAMBLE COMPANY (US) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000040210-A2 | TOPICAL COMPOSITIONS COMPRISING PROTECTED FUNCTIONAL THIOLS | THE PROCTER & GAMBLE COMPANY (US) | 2000-07-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020012639-A1 | May be used in hair care, textile care, cosmetics, oral care formulations, skin, nail, laundry, acne care formulations | SCLY, TST, SRR | CYP3A4 1463/4885CA9 3325/4885CA1 3937/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.