Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.57 |
| ▸ | PKM | P14618 | 4/20 | 0.56 |
| ▸ | MMP1 | P03956 | 2/20 | 0.53 |
| ▸ | MMP2 | P08253 | 2/20 | 0.53 |
| ▸ | MMP9 | P14780 | 2/20 | 0.53 |
| ▸ | MMP13 | P45452 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | MMP8 | P22894 | 1/20 | 0.53 |
| ▸ | MMP3 | P08254 | 1/20 | 0.53 |
| ▸ | MMP7 | P09237 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2007611 | 0.95 | GAA (0.59) | GAAALDH1A1SIGMAR1PKMMMP1 | |
| SCHEMBL5499591 | 0.93 | ALDH1A1 (0.59) | GAAALDH1A1SIGMAR1PKMMMP1 | |
| SCHEMBL2013273 | 0.93 | ALDH1A1 (0.59) | GAAALDH1A1SIGMAR1PKMMMP1 | |
| SCHEMBL2009051 | 0.90 | MMP2 (0.59) | GAAALDH1A1SIGMAR1PKMMMP1 | |
| SCHEMBL1348420 | 0.89 | ALDH1A1 (0.64) | GAAALDH1A1SIGMAR1PKMMMP1 | |
| SCHEMBL12570903 | 0.89 | MMP2 (0.57) | GAAALDH1A1SIGMAR1PKMMMP1 | |
| SCHEMBL9780583 | 0.87 | ALDH1A1 (0.67) | GAAALDH1A1SIGMAR1PKMMMP1 | |
| SCHEMBL9577239 | 0.85 | SIGMAR1 (0.68) | GAAALDH1A1SIGMAR1PKMMMP1 | |
| SCHEMBL10462666 | 0.84 | TBXA2R (0.60) | ALDH1A1CA1CA2KMT2ATDP1 | |
| SCHEMBL4703731 | 0.82 | CA12 (0.71) | GAAALDH1A1PKMCA2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070149508-A1 | Six membered heteroaromatic inhibitors targeting resistant kinase mutations | TARGEGEN, INC. (US) | 2007-06-28 | — | — | US | disclosed |
| US-20070149508-A1 | Six membered heteroaromatic inhibitors targeting resistant kinase mutations | TARGEGEN, INC. (US) | 2007-06-28 | — | — | US | disclosed |
| US-20070149508-A1 | Six membered heteroaromatic inhibitors targeting resistant kinase mutations | TARGEGEN, INC. (US) | 2007-06-28 | — | — | US | disclosed |
| US-6365605-B1 | ADMINISTERING D.SUB.3 RECEPTOR LIGAND FOR THERAPY OF CONDITIONS SELECTED FROM DEPRESSION, SCHIZOPHRENIA, PSYCHOSES, PARKINSONS'S DISEASE, MEMORY DISORDERS, AND DISORDERS ASSOCIATED WITH DRUG ABUSE | LES LABORATOIRES SERVIER (FR) | 2002-04-02 | — | — | US | disclosed |
| US-6326377-B1 | PSYCHOLOGICAL DISORDERS THERAPY | ADIR ET COMPAGNIE (FR) | 2001-12-04 | — | — | US | disclosed |
| EP-0887350-B1 | Chromene derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-08-22 | — | — | EP | disclosed |
| US-6090837-A | PSYCHOLOGICAL DISORDERS | ADIR ET COMPAGNIE (FR) | 2000-07-18 | — | — | US | disclosed |
| EP-0887350-A1 | Chromene derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-12-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070149508-A1 | Six membered heteroaromatic inhibitors targeting resistant kinase mutations | ABL1, KDR, BCR | GAA 1753/4885ALDH1A1 3322/4885SIGMAR1 3487/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.