Dithiothreitol

Dithiothreitol

SCHEMBL28079600

OCCS.O[C@@H](CS)[C@@H](O)CS

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.42
TDP1 Q9NUW8 2/20 0.35
NR1I2 O75469 1/20 0.35
ALDH1A1 P00352 1/20 0.35
CYP1A2 P05177 1/20 0.35
HTT P42858 1/20 0.35
HSD17B10 Q99714 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dl-Dithiothreitol SCHEMBL27262405 1.00 LMNA (0.42) LMNATDP1NR1I2ALDH1A1CYP1A2
Dl-Dithiothreitol SCHEMBL2052829 1.00 LMNA (0.42) LMNATDP1NR1I2ALDH1A1CYP1A2
Dl-Dithiothreitol SCHEMBL78921 0.84
Dl-Dithiothreitol SCHEMBL21114401 0.84 LMNA (0.44) LMNATDP1NR1I2ALDH1A1CYP1A2
Dl-Dithiothreitol SCHEMBL17370231 0.84
Dl-Dithiothreitol SCHEMBL14496668 0.84
Dithiothreitol SCHEMBL538995 0.84
Dl-Dithiothreitol SCHEMBL21114400 0.84 LMNA (0.44) LMNATDP1NR1I2ALDH1A1CYP1A2
Dl-Dithiothreitol SCHEMBL87345 0.84
Dl-Dithiothreitol SCHEMBL10601 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105766990-B As preservative for agricultural, bismuth-mercaptan of industry and other purposes 微生物公司 2019-08-02 CN disclosed
CN-105766990-A Bismuth-thiols As Antiseptics For Epithelial Tissues, Acute And Chronic Wounds, Bacterial Biofilms And Other Indications 微生物公司 2016-07-20 CN disclosed