SCHEMBL28079925

SCHEMBL28079925

C=COC(=O)c1cccc(C(=O)OC=C)c1C(=O)OC=C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.46
ALDH1A1 P00352 4/20 0.40
TSHR P16473 3/20 0.40
HSD17B10 Q99714 2/20 0.40
CA12 O43570 3/20 0.34
CA1 P00915 3/20 0.34
CA2 P00918 3/20 0.34
CA7 P43166 3/20 0.34
CA9 Q16790 3/20 0.34
CA14 Q9ULX7 3/20 0.34
KMT2A Q03164 1/20 0.34
PLAU P00749 1/20 0.33
KDM4E B2RXH2 2/20 0.32
MAPT P10636 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
LMNA P02545 1/20 0.31
ALOX15 P16050 1/20 0.31
NPC1 O15118 1/20 0.31
LIG1 P18858 1/20 0.31
CFTR P13569 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15175 0.85 CYP3A4 (0.55) CYP3A4ALDH1A1TSHRHSD17B10KDM4E
SCHEMBL7943455 0.83 CYP3A4 (0.37) CYP3A4ALDH1A1TSHRHSD17B10CA12
Ethylene SCHEMBL29113890 0.83 CYP3A4 (0.53) CYP3A4ALDH1A1TSHRHSD17B10KDM4E
SCHEMBL7785438 0.80 KDM4E (0.53) CYP3A4ALDH1A1TSHRHSD17B10KMT2A
SCHEMBL8850990 0.80 CYP3A4 (0.40) CYP3A4ALDH1A1TSHRHSD17B10CA12
SCHEMBL29197935 0.79 CYP3A4 (0.50) CYP3A4ALDH1A1TSHRHSD17B10TDP1
SCHEMBL19506917 0.79 CYP3A4 (0.46) CYP3A4ALDH1A1TSHRHSD17B10KDM4E
SCHEMBL220576 0.78 ALDH1A1 (0.56) CYP3A4ALDH1A1TSHRHSD17B10CA12
SCHEMBL194863 0.78 TSHR (0.57) CYP3A4ALDH1A1TSHRHSD17B10CA12
SCHEMBL2834918 0.78 CES2 (0.50) KMT2AKDM4ETDP1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103339083-B Powdery accelerator 建筑研究和技术有限公司 2016-11-09 CN disclosed
CN-103339083-A Powdered accelerator CONSTR RES & TECH GMBH 2013-10-02 CN disclosed
CN-1210870-A Water-swellable elastomer composition SHOWA DENKO KK (JP) 1999-03-17 CN disclosed