Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | HPGD | P15428 | 5/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 7/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 6/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27163023 | 0.78 | ALDH1A1 (0.39) | ALDH1A1HPGDLMNAMEN1KMT2A | |
| SCHEMBL30026940 | 0.78 | ALDH1A1 (0.39) | ALDH1A1HPGDLMNAMEN1KMT2A | |
| SCHEMBL7483940 | 0.78 | KDM4E (0.47) | ALDH1A1HPGDLMNAMEN1KMT2A | |
| SCHEMBL21858235 | 0.76 | ALDH1A1 (0.38) | ALDH1A1HPGDLMNAMEN1KMT2A | |
| SCHEMBL28996788 | 0.75 | ALDH1A1 (0.40) | ALDH1A1HPGDLMNAMEN1KMT2A | |
| SCHEMBL10638399 | 0.75 | ALDH1A1 (1.00) | ALDH1A1HPGDLMNAMEN1KMT2A | |
| SCHEMBL7813204 | 0.71 | ALDH1A1 (0.42) | ALDH1A1HPGDLMNAMEN1KMT2A | |
| SCHEMBL24715944 | 0.70 | ALDH1A1 (0.50) | ALDH1A1HPGDLMNAMEN1KMT2A | |
| SCHEMBL29019083 | 0.70 | ALDH1A1 (0.63) | ALDH1A1HPGDLMNAMEN1KMT2A | |
| SCHEMBL19744049 | 0.70 | GPR35 (0.59) | ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105777691-A | 6-fluoro-8-methoxy chromene-4-one and synthesis method thereof | 江苏理工学院 | 2016-07-20 | — | — | CN | disclosed |
| CN-105777691-A | 6-fluoro-8-methoxy chromene-4-one and synthesis method thereof | 江苏理工学院 | 2016-07-20 | — | — | CN | disclosed |