Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 3/20 | 0.49 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.48 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | AHR | P35869 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL845701 | 0.90 | KMT2A (0.62) | KMT2AL3MBTL1ALDH1A1TDP1KDM4E | |
| SCHEMBL29729685 | 0.90 | KMT2A (0.62) | KMT2AL3MBTL1ALDH1A1TDP1KDM4E | |
| Pyridine SCHEMBL28203867 | 0.86 | L3MBTL1 (0.57) | L3MBTL1ALDH1A1TDP1KDM4EHTT | |
| SCHEMBL4021165 | 0.82 | ROS1 (0.51) | KMT2AALDH1A1KDM4EHTTMEN1 | |
| SCHEMBL28332298 | 0.82 | KMT2A (0.53) | KMT2AL3MBTL1ALDH1A1TDP1KDM4E | |
| SCHEMBL8366149 | 0.79 | KMT2A (0.56) | KMT2AL3MBTL1ALDH1A1TDP1KDM4E | |
| SCHEMBL30070191 | 0.79 | KMT2A (0.56) | KMT2AL3MBTL1ALDH1A1TDP1KDM4E | |
| SCHEMBL10810930 | 0.79 | L3MBTL1 (0.57) | KMT2AL3MBTL1ALDH1A1TDP1KDM4E | |
| SCHEMBL21693940 | 0.76 | TDP1 (0.61) | KMT2AL3MBTL1ALDH1A1TDP1KDM4E | |
| SCHEMBL11304824 | 0.76 | TDP1 (0.61) | KMT2AL3MBTL1ALDH1A1TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105777618-A | Naphthylacetic acid pyridine ethyl ester compounds and use thereof | 青岛科技大学 | 2016-07-20 | — | — | CN | disclosed |
| CN-105777618-A | Naphthylacetic acid pyridine ethyl ester compounds and use thereof | 青岛科技大学 | 2016-07-20 | — | — | CN | disclosed |