SCHEMBL845701

SCHEMBL845701

CCOC(=O)Cc1cccc2ccccc12

nearest known ligand 0.62

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.62
L3MBTL1 Q9Y468 6/20 0.60
TDP1 Q9NUW8 3/20 0.60
PKM P14618 3/20 0.57
SIRT5 Q9NXA8 1/20 0.57
LMNA P02545 1/20 0.56
KDM4E B2RXH2 2/20 0.55
APOBEC3A P31941 1/20 0.55
APOBEC3G Q9HC16 1/20 0.55
ALDH1A1 P00352 2/20 0.54
HPGD P15428 2/20 0.54
MAPT P10636 1/20 0.54
ATM Q13315 1/20 0.54
CYP4F2 P78329 1/20 0.51
CYP4A11 Q02928 1/20 0.51
CDC25B P30305 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29729685 1.00 KMT2A (0.62) KMT2AL3MBTL1TDP1PKMSIRT5
SCHEMBL28332298 0.91 KMT2A (0.53) KMT2AL3MBTL1TDP1PKMSIRT5
Pyridine SCHEMBL28079953 0.90 KMT2A (0.53) KMT2AL3MBTL1TDP1PKMSIRT5
SCHEMBL8366149 0.88 KMT2A (0.56) KMT2AL3MBTL1TDP1PKMSIRT5
SCHEMBL30070191 0.88 KMT2A (0.56) KMT2AL3MBTL1TDP1PKMSIRT5
SCHEMBL10810930 0.87 L3MBTL1 (0.57) KMT2AL3MBTL1TDP1PKMSIRT5
SCHEMBL11304824 0.85 TDP1 (0.61) KMT2AL3MBTL1TDP1PKMSIRT5
SCHEMBL21693940 0.85 TDP1 (0.61) KMT2AL3MBTL1TDP1PKMSIRT5
SCHEMBL15305557 0.84 L3MBTL1 (0.50) KMT2AL3MBTL1TDP1PKMSIRT5
SCHEMBL26148314 0.84 L3MBTL1 (0.58) KMT2AL3MBTL1TDP1PKMSIRT5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 637 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3174865-B1 MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2020-12-09 EP claimed
WO-2020154349-A1 METHODS AND FORMULATIONS FOR PREVENTING DOWNWARD MIGRATION OF AGRICULTURAL MATERIALS BAYER CROPSCIENCE LP (US) 2020-07-30 WO claimed
US-20200236925-A1 METHODS AND FORMULATIONS FOR PREVENTING DOWNWARD MIGRATION OF AGRICULTURAL MATERIALS DISCOVERY PURCHASER CORPORATION 2020-07-30 US claimed
US-RE48057-E1 Pesticidal compositions and related methods DOW AGROSCIENCES LLC (US) 2020-06-23 US claimed
CN-111011381-A Seed treatment agent for improving lodging resistance and yield of quinoa 四川省农业科学院生物技术核技术研究所 2020-04-17 CN claimed
US-20200055846-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2020-02-20 US claimed
EP-3145312-B1 PESTICIDAL COMPOSITIONS AND RELATED METHODS DOW AGROSCIENCES LLC (US) 2019-11-20 EP claimed
EP-3160943-B1 MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2019-09-18 EP claimed
EP-3062619-B1 PESTICIDAL COMPOSITIONS AND RELATED METHODS DOW AGROSCIENCES LLC (US) 2019-07-24 EP claimed
CN-105682461-B Pesticidal combination and relative method 美国陶氏益农公司 2019-06-14 CN claimed
WO-2012177813-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2012-12-27 WO claimed
US-20120329649-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC 2012-12-27 US claimed
WO-2012061290-A2 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2012-05-10 WO claimed
WO-2012061288-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2012-05-10 WO claimed
US-20120110701-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2012-05-03 US claimed
US-20120110702-A1 Pesticidal Compositions and Processes Related Thereto CORTEVA AGRISCIENCE LLC 2012-05-03 US claimed
US-20110152077-A1 Active compound combinations BAYER CROPSCIENCE AG (DE) 2011-06-23 US claimed
US-20080242544-A1 Phytoactive Composition MICAP PLC (GB) 2008-10-02 US claimed
EP-1750504-A1 PHYTOACTIVE COMPOSITION MICAP PLC. (GB) 2007-02-14 EP claimed
WO-2005102045-A1 PHYTOACTIVE COMPOSITION MICAP PLC (GB) 2005-11-03 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110152077-A1 Active compound combinations BROX, ATL3, AKR7A2 KMT2A 3664/4885L3MBTL1 549/4885TDP1 3783/4885
US-20080242544-A1 Phytoactive Composition PNMT, ACHE, TACR1 KMT2A 2713/4885L3MBTL1 4828/4885TDP1 2681/4885
US-20120110701-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO ACHE, AGPS, DDT KMT2A 3634/4885L3MBTL1 3817/4885TDP1 2045/4885
US-20120329649-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO ACHE, DDT, PTMS KMT2A 3494/4885L3MBTL1 3693/4885TDP1 2276/4885
US-20200055846-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO ACHE, DDT, PTMS KMT2A 3565/4885L3MBTL1 3896/4885TDP1 2067/4885
US-20120110702-A1 Pesticidal Compositions and Processes Related Thereto ACHE, DDT, PTMS KMT2A 3565/4885L3MBTL1 3896/4885TDP1 2067/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.