Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23216476 | 0.90 | HRH3 (0.38) | OPRM1OPRL1OPRK1OPRD1HRH3 | |
| SCHEMBL2586838 | 0.84 | ALDH1A1 (0.44) | OPRM1OPRL1 | |
| SCHEMBL743233 | 0.82 | MEN1 (0.36) | OPRM1OPRL1 | |
| SCHEMBL29971918 | 0.77 | OPRM1 (0.33) | OPRM1OPRL1 | |
| SCHEMBL18128230 | 0.75 | OPRM1 (0.33) | OPRM1OPRL1HRH3PDK2 | |
| SCHEMBL13920507 | 0.74 | OPRM1 (0.34) | OPRM1OPRL1OPRK1OPRD1HRH3 | |
| SCHEMBL27466823 | 0.72 | APLNR (0.35) | OPRM1OPRL1OPRK1PDK2 | |
| SCHEMBL24455261 | 0.70 | OPRM1 (0.60) | OPRM1OPRL1OPRK1OPRD1HRH3 | |
| SCHEMBL4813101 | 0.69 | OPRM1 (0.41) | OPRM1OPRL1HRH3GRIN2B | |
| Hydrochloric Acid SCHEMBL2588318 | 0.68 | OPRM1 (0.40) | OPRM1OPRL1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024249642-A1 | EGFR INHIBITORS | ACERAND THERAPEUTICS (HONG KONG) LIMITED (CN) | 2024-12-05 | — | — | WO | disclosed |
| CN-105814022-B | Condensed bicyclic heteroaromatic derivative as TNF active regulators | UCB生物制药私人有限公司 | 2018-09-28 | — | — | CN | disclosed |
| CN-105814054-B | Condensed imidazole and pyrazole derivatives as TNF active regulators | UCB生物制药私人有限公司 | 2018-09-25 | — | — | CN | disclosed |
| CN-107787319-A | Indazole derivatives as modulators of TNF activity | UCB生物制药私人有限公司 | 2018-03-09 | — | — | CN | disclosed |
| CN-105814054-A | Fused imidazole and pyrazole derivatives as modulators of TNF activity | UCB生物制药私人有限公司 | 2016-07-27 | — | — | CN | disclosed |
| CN-105814022-A | Fused bicyclic heteroaromatic derivatives as modulators of tnf activity | UCB生物制药私人有限公司 | 2016-07-27 | — | — | CN | disclosed |