SCHEMBL28080049

SCHEMBL28080049

COc1cc(F)cc2c1OCC=C2

nearest known ligand 0.51

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28445449 0.81 CA12 (0.34)
SCHEMBL30991565 0.77 CA1 (0.32)
SCHEMBL30094394 0.77 CYP3A4 (0.42)
SCHEMBL1478443 0.74 ADRA2A (0.38)
SCHEMBL7520140 0.72 KMT2A (0.43) NFE2L2
SCHEMBL9112587 0.71 CYP2B6 (0.39)
SCHEMBL30098731 0.71 KDM4E (0.42)
SCHEMBL17186171 0.68 STS (0.41)
SCHEMBL25209139 0.67 MEN1 (0.31)
SCHEMBL1477835 0.67 LMNA (0.34) NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105777691-A 6-fluoro-8-methoxy chromene-4-one and synthesis method thereof 江苏理工学院 2016-07-20 CN disclosed