Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HMGCR | P04035 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3422296 | 0.83 | KMT2A (0.48) | MEN1KMT2ACYP3A4PTGS1DRD3 | |
| SCHEMBL16284311 | 0.81 | CYP3A4 (0.63) | MEN1KMT2ACYP3A4PTGS1DRD3 | |
| SCHEMBL28475334 | 0.81 | HDAC1 (0.31) | HDAC1HDAC6 | |
| SCHEMBL27788907 | 0.79 | TSHR (0.46) | MEN1KMT2ACYP3A4PTGS1DRD3 | |
| SCHEMBL27841431 | 0.79 | MEN1 (0.45) | MEN1KMT2ACYP3A4PTGS1DRD3 | |
| SCHEMBL9634983 | 0.77 | KMT2A (0.47) | MEN1KMT2ACYP3A4PTGS1DRD3 | |
| SCHEMBL28091408 | 0.76 | KMT2A (0.49) | MEN1KMT2ACYP3A4PTGS1DRD3 | |
| SCHEMBL6192201 | 0.76 | KMT2A (0.39) | MEN1KMT2ACYP3A4MAPTTSHR | |
| SCHEMBL14047784 | 0.75 | HSP90AB1 (0.46) | MEN1KMT2ACYP3A4MAPTALDH1A1 | |
| SCHEMBL1457528 | 0.75 | ALDH1A1 (0.52) | KMT2ACYP3A4MAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104529904-B | The preparation method of Bo Maxini | 苏州明锐医药科技有限公司 | 2016-08-31 | — | — | CN | disclosed |