Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Lysine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 2/20 | 1.00 |
| ▸ | ARG2 | P78540 | 4/20 | 0.59 |
| ▸ | ARG1 | P05089 | 3/20 | 0.59 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.52 |
| ▸ | GRM8 | O00222 | 1/20 | 0.52 |
| ▸ | GRM6 | O15303 | 1/20 | 0.52 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.52 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.52 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.52 |
| ▸ | GRM5 | P41594 | 1/20 | 0.52 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.52 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.52 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.52 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.52 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.52 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.52 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.52 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.52 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lysine SCHEMBL2802757 | 1.00 | GSR (1.00) | GSRARG2ARG1RNPEPCYP1A2 | |
| Lysine SCHEMBL8613373 | 1.00 | GSR (1.00) | GSRARG2ARG1RNPEPCYP1A2 | |
| Lysine SCHEMBL3359527 | 1.00 | GSR (1.00) | GSRARG2ARG1RNPEPCYP1A2 | |
| Lysine SCHEMBL1645 | 1.00 | GSR (1.00) | GSRARG2ARG1RNPEPCYP1A2 | |
| Lysine SCHEMBL12867528 | 1.00 | GSR (1.00) | GSRARG2ARG1RNPEPCYP1A2 | |
| Lysine SCHEMBL1000151 | 1.00 | GSR (1.00) | GSRARG2ARG1RNPEPCYP1A2 | |
| Lysine SCHEMBL9439278 | 1.00 | GSR (1.00) | GSRARG2ARG1RNPEPCYP1A2 | |
| Lysine SCHEMBL20362357 | 1.00 | GSR (1.00) | GSRARG2ARG1RNPEPCYP1A2 | |
| Lysine SCHEMBL7343 | 1.00 | GSR (1.00) | GSRARG2ARG1RNPEPCYP1A2 | |
| Lysine SCHEMBL15303774 | 1.00 | GSR (1.00) | GSRARG2ARG1RNPEPCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1520073-B1 | TRIAZINNYLAMINOSTILBENE DISULPHONIC ACID MIXTURES | BASF SE (DE) | 2012-01-18 | — | — | EP | claimed |
| US-20110286915-A1 | Nanocarriers for Drug Delivery | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-11-24 | — | — | US | claimed |
| EP-2344134-A2 | NANOCARRIERS FOR DRUG DELIVERY | The Regents of the University of California (US) | 2011-07-20 | — | — | EP | claimed |
| EP-2292837-A1 | Triazinylaminostilbene disulphonic acid mixtures | BASF SE (DE) | 2011-03-09 | — | — | EP | claimed |
| WO-2012052096-A1 | METHOD TO CONTROL AND VALIDATE THE QUALITY OF QUANTITATIVE ANALYSIS OF BIOLOGICAL SAMPLES | METABOLOMIC DISCOVERIES GMBH (DE) | 2012-04-26 | — | — | WO | disclosed |
| EP-1520073-B1 | TRIAZINNYLAMINOSTILBENE DISULPHONIC ACID MIXTURES | BASF SE (DE) | 2012-01-18 | — | — | EP | disclosed |
| US-20110286915-A1 | Nanocarriers for Drug Delivery | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-11-24 | — | — | US | disclosed |
| US-8044166-B2 | Process for preparing pentamethylene 1,5-diisocyanate | BASF AKTIENGESELLSCHAFT (DE) | 2011-10-25 | — | — | US | disclosed |
| EP-2344134-A2 | NANOCARRIERS FOR DRUG DELIVERY | The Regents of the University of California (US) | 2011-07-20 | — | — | EP | disclosed |
| US-7914979-B2 | Preparing preservative mixture for storage of newcastle disease virus | WELLSTAT BIOLOGICS CORPORATION (US) | 2011-03-29 | — | — | US | disclosed |
| US-7911035-B2 | Directionally controlled growth of nanowhiskers | QUNANO AB (SE) | 2011-03-22 | — | — | US | disclosed |
| EP-2292837-A1 | Triazinylaminostilbene disulphonic acid mixtures | BASF SE (DE) | 2011-03-09 | — | — | EP | disclosed |
| US-20110033517-A1 | COATINGS FOR IMPLANTABLE MEDICAL DEVICES COMPRISING HYDROPHILIC SUBSTANCES AND METHODS FOR FABRICATING THE SAME | ADVANCED CARDIOVASCULAR SYSTEMS, INC. | 2011-02-10 | — | — | US | disclosed |
| EP-0487632-A1 | STABILIZED VACCINE COMPOSITIONS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1992-06-03 | — | — | EP | disclosed |
| WO-1991002543-A1 | STABILIZED VACCINE COMPOSITIONS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1991-03-07 | — | — | WO | disclosed |
| US-3994688-A | REACTING L-LYSINE WITH A G-FORMYL-PYRIDINE DERIVATIVE | A/S N. FOSS ELECTRIC (DK) | 1976-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110033517-A1 | COATINGS FOR IMPLANTABLE MEDICAL DEVICES COMPRISING HYDROPHILIC SUBSTANCES AND METHODS FOR FABRICATING THE SAME | CD99, CD44, PUF60 | GSR 4336/4885ARG2 3137/4885ARG1 617/4885 |
| US-20110286915-A1 | Nanocarriers for Drug Delivery | CLTA, EPCAM, EGFR | GSR 1966/4885ARG2 2821/4885ARG1 3516/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.