Formamide

Formamide

SCHEMBL28080784

CS(=O)(=O)c1ccccc1[N+](=O)[O-].NC=O

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.59
MEN1 O00255 3/20 0.59
CA1 P00915 1/20 0.51
CA2 P00918 1/20 0.51
MMP1 P03956 1/20 0.51
MMP2 P08253 1/20 0.51
MMP9 P14780 1/20 0.51
MMP8 P22894 1/20 0.51
MMP13 P45452 1/20 0.51
F2 P00734 3/20 0.51
PRSS1 P07477 3/20 0.51
PRSS2 P07478 3/20 0.51
PRSS3 P35030 3/20 0.51
HPGD P15428 2/20 0.48
THRB P10828 3/20 0.48
PKM P14618 1/20 0.47
ALDH1A1 P00352 4/20 0.46
POLB P06746 2/20 0.46
ACHE P22303 1/20 0.46
LMNA P02545 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2913624 0.91 KMT2A (0.70) KMT2AMEN1CA1CA2MMP1
Phenol SCHEMBL28298827 0.81 KMT2A (0.58) KMT2AMEN1CA1CA2MMP1
SCHEMBL20150197 0.77 KMT2A (0.66) KMT2AMEN1CA1CA2MMP1
SCHEMBL4158554 0.76 KMT2A (0.70) KMT2AMEN1CA1CA2MMP1
SCHEMBL370668 0.76 KMT2A (0.70) KMT2AMEN1CA1CA2MMP1
SCHEMBL11566827 0.75 KMT2A (1.00) KMT2AMEN1CA1CA2MMP1
SCHEMBL30446303 0.75 KMT2A (1.00) KMT2AMEN1CA1CA2MMP1
SCHEMBL2039879 0.75 KMT2A (1.00) KMT2AMEN1CA1CA2MMP1
SCHEMBL5144345 0.75 KMT2A (0.63) KMT2AMEN1CA1CA2MMP1
SCHEMBL9356245 0.75 TDP1 (0.64) KMT2AMEN1CA1CA2MMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105861358-A Fomesafen degrading bacterium and application thereof 浙江大学 2016-08-17 CN disclosed