SCHEMBL2913624

SCHEMBL2913624

CS(=O)(=O)c1ccccc1[N+](=O)[O-]

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.70
MEN1 O00255 2/20 0.70
CA1 P00915 1/20 0.59
CA2 P00918 1/20 0.59
MMP1 P03956 1/20 0.59
MMP2 P08253 1/20 0.59
MMP9 P14780 1/20 0.59
MMP8 P22894 1/20 0.59
MMP13 P45452 1/20 0.59
F2 P00734 3/20 0.54
PRSS1 P07477 3/20 0.54
PRSS2 P07478 3/20 0.54
PRSS3 P35030 3/20 0.54
THRB P10828 3/20 0.54
ALDH1A1 P00352 3/20 0.53
PKM P14618 1/20 0.53
HSD17B10 Q99714 1/20 0.52
ACHE P22303 1/20 0.51
LMNA P02545 1/20 0.51
POLB P06746 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formamide SCHEMBL28080784 0.91 KMT2A (0.59) KMT2AMEN1CA1CA2MMP1
Phenol SCHEMBL28298827 0.89 KMT2A (0.58) KMT2AMEN1CA1CA2MMP1
SCHEMBL20150197 0.84 KMT2A (0.66) KMT2AMEN1CA1CA2MMP1
SCHEMBL30446303 0.83 KMT2A (1.00) KMT2AMEN1CA1CA2MMP1
SCHEMBL2039879 0.83 KMT2A (1.00) KMT2AMEN1CA1CA2MMP1
SCHEMBL11566827 0.83 KMT2A (1.00) KMT2AMEN1CA1CA2MMP1
SCHEMBL9356245 0.82 TDP1 (0.64) KMT2AMEN1CA1CA2MMP1
SCHEMBL20150195 0.81 KMT2A (0.61) KMT2AMEN1CA1CA2MMP1
SCHEMBL237684 0.81 KMT2A (0.73) KMT2AMEN1CA1CA2MMP1
SCHEMBL1340928 0.81 L3MBTL1 (0.61) KMT2AMEN1CA1CA2MMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12448368-B2 Indole compounds as androgen receptor modulators NIDO BIOSCIENCES, INC. (US) 2025-10-21 US disclosed
US-20250122176-A1 INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS NIDO BIOSCIENCES INC (US) 2025-04-17 US disclosed
US-20250092021-A9 INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS NIDO BIOSCIENCES, INC. 2025-03-20 US disclosed
EP-4384510-A1 COMPOUNDS TARGETING MUTANT OF P53 Jacobio Pharmaceuticals Co., Ltd. (CN) 2024-06-19 EP disclosed
WO-2024041503-A1 COMPOUNDS TARGETING Y220C MUTANT OF P53 JACOBIO PHARMACEUTICALS CO., LTD. (CN) 2024-02-29 WO disclosed
WO-2024015958-A1 CYCLIC PEPTIDE INHIBITORS OF IL-23 JANSSEN PHARMACEUTICA NV (BE) 2024-01-18 WO disclosed
US-20230348439-A1 INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS NIDO BIOSCIENCES INC (US) 2023-11-02 US disclosed
US-11667624-B2 Indole compounds as androgen receptor modulators NIDO BIOSCIENCES, INC. (US) 2023-06-06 US disclosed
EP-4182320-A1 INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS Nido Biosciences, Inc. (US) 2023-05-24 EP disclosed
CN-115996926-A Indole compounds as androgen receptor modulators 尼多生物科学有限公司 2023-04-21 CN disclosed
US-5856273-A CONTROLLING WEEDS ZENECA LIMITED (GB) 1999-01-05 US disclosed
EP-0672038-A1 HERBICIDES ZENECA LIMITED (GB) 1995-09-20 EP disclosed
WO-1994013652-A1 HERBICIDES ZENECA LIMITED (GB) 1994-06-23 WO disclosed
US-5101047-A Sulfobetaine-substituted α-sulfonylcarboxylic acids from diallylammonium salts and a process for the preparation thereof BALLSCHUH DETLEF (DE) 1992-03-31 US disclosed
US-5099043-A 3-METHYLSULFONYLMETHYL-4-SULFOMETHYL-PYRROLIDINIUM-BETAINES AND PROCESS FOR THEIR PREPARATION BALLSCHUH DETLEF (DE) 1992-03-24 US disclosed
EP-0434174-A1 3-Methylsulfonylmethyl-4-sulfomethyl-pyrrolidinium betains and process for their preparation INSTITUT FÜR CHEMISCHE TECHNOLOGIE (DE) 1991-06-26 EP disclosed
EP-0434175-A1 Sulphobetain-substituted alpha-sulphonyl carboxylic acids from diallylammonium salts and process for their preparation INSTITUT FÜR CHEMISCHE TECHNOLOGIE (DE) 1991-06-26 EP disclosed
EP-0039312-B1 COLOUR PHOTOPGRAPHIC MATERIAL FOR THE SILVER-DYE BLEACHING PROCESS, PROCESS FOR THE PRODUCTION OF THIS MATERIAL AND ITS USE IN THE PRODUCTION OF PHOTOGRAPHIC IMAGES CIBA-GEIGY AG (CH) 1983-12-28 EP disclosed
US-4379819-A OIL SOLUBLE MONOAZO DYE CIBA-GEIGY AG (CH) 1983-04-12 US disclosed
EP-0039312-A1 Colour photopgraphic material for the silver-dye bleaching process, process for the production of this material and its use in the production of photographic images CIBA-GEIGY AG (CH) 1981-11-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230348439-A1 INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS AR, FSHR, NR5A1 KMT2A 1683/4885MEN1 2673/4885CA1 4769/4885
US-20250122176-A1 INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS AR, FSHR, NR5A1 KMT2A 1853/4885MEN1 2818/4885CA1 4733/4885
US-11667624-B2 Indole compounds as androgen receptor modulators AR, FSHR, ADRB3 KMT2A 1758/4885MEN1 2646/4885CA1 4739/4885
US-20250092021-A9 INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS AR, FSHR, NR5A1 KMT2A 1853/4885MEN1 2818/4885CA1 4733/4885
US-12448368-B2 Indole compounds as androgen receptor modulators AR, FSHR, ADRB3 KMT2A 1758/4885MEN1 2646/4885CA1 4739/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.