Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | MMP1 | P03956 | 1/20 | 0.54 |
| ▸ | MMP2 | P08253 | 1/20 | 0.54 |
| ▸ | MMP9 | P14780 | 1/20 | 0.54 |
| ▸ | MMP8 | P22894 | 1/20 | 0.54 |
| ▸ | MMP13 | P45452 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | F2 | P00734 | 3/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2913624 | 0.89 | KMT2A (0.70) | KMT2AMEN1CA1CA2MMP1 | |
| Formamide SCHEMBL28080784 | 0.81 | KMT2A (0.59) | KMT2AMEN1CA1CA2MMP1 | |
| Phenol SCHEMBL27289892 | 0.80 | GPR35 (0.60) | KMT2AMEN1CA1CA2ALDH1A1 | |
| SCHEMBL20150197 | 0.79 | KMT2A (0.66) | KMT2AMEN1CA1CA2MMP1 | |
| SCHEMBL10898132 | 0.78 | KMT2A (0.77) | KMT2AMEN1CA1CA2MMP1 | |
| SCHEMBL3870146 | 0.76 | VCAM1 (0.59) | KMT2ACA1CA2THRBPKM | |
| SCHEMBL11879430 | 0.76 | VCAM1 (0.48) | KMT2AMEN1CA1CA2MMP1 | |
| Phenol SCHEMBL27921335 | 0.75 | HSD17B10 (0.77) | KMT2AMEN1ALDH1A1GAATDP1 | |
| Phenol SCHEMBL27514399 | 0.75 | GPR35 (0.50) | KMT2AMEN1CA1CA2MMP1 | |
| Nitrophenolate SCHEMBL10540580 | 0.74 | GPR35 (0.57) | KMT2AMEN1CA1CA2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109715625-A | Crystalline solid forms of BET inhibitors | 因赛特公司 | 2019-05-03 | — | — | CN | disclosed |