SCHEMBL28080962

SCHEMBL28080962

O=P(O)(O)c1c(-c2ccccc2)[nH]c2ccc(Cl)cc12

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.51
KMT2A Q03164 3/20 0.51
RXFP1 Q9HBX9 1/20 0.51
MAP2 P11137 3/20 0.51
KDM4E B2RXH2 3/20 0.50
PTGS2 P35354 2/20 0.50
ALDH1A1 P00352 2/20 0.50
PDE10A Q9Y233 1/20 0.50
CASP1 P29466 1/20 0.48
NPSR1 Q6W5P4 1/20 0.48
HSD17B10 Q99714 1/20 0.48
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
ROCK2 O75116 1/20 0.47
MAP4K4 O95819 1/20 0.47
LCK P06239 1/20 0.47
CSF1R P07333 1/20 0.47
PIM1 P11309 1/20 0.47
RPS6KB1 P23443 1/20 0.47
CDK2 P24941 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1074359 0.83 NPSR1 (0.60) MEN1KMT2AKDM4EALDH1A1NPSR1
SCHEMBL28171931 0.83 HPGD (0.51) MEN1KMT2AKDM4EPTGS2ALDH1A1
SCHEMBL13550372 0.75 KDM4E (0.62) MEN1KMT2ARXFP1MAP2KDM4E
SCHEMBL7039216 0.75 PTGS2 (0.72) MEN1KMT2ARXFP1MAP2KDM4E
SCHEMBL6300664 0.74 PDE10A (0.60) MEN1KMT2ARXFP1MAP2KDM4E
SCHEMBL29090134 0.74 F2 (0.58) MEN1KMT2ARXFP1MAP2KDM4E
SCHEMBL11584079 0.74 PTGS2 (0.55) MEN1KMT2ARXFP1MAP2KDM4E
SCHEMBL28906438 0.73 TUBB4A (0.67) MEN1KMT2ARXFP1MAP2KDM4E
SCHEMBL8020349 0.72 PDE10A (0.64) MEN1KMT2ARXFP1MAP2KDM4E
SCHEMBL28833412 0.72 PDE10A (0.71) MEN1KMT2ARXFP1MAP2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105884825-A Method for synthesizing indole-3-phosphonate 南京林业大学 2016-08-24 CN disclosed