Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GALR2 | O43603 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSH | P09668 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25826451 | 0.81 | MEN1 (0.38) | TSHRCYP3A4ALDH1A1RECQLTDP1 | |
| SCHEMBL111594 | 0.77 | ALDH1A1 (0.41) | TSHRCYP3A4ALDH1A1RECQLTDP1 | |
| SCHEMBL29868909 | 0.77 | ALDH1A1 (0.41) | TSHRCYP3A4ALDH1A1RECQLTDP1 | |
| SCHEMBL28073294 | 0.76 | ALDH1A1 (0.39) | TSHRCYP3A4ALDH1A1RECQLTDP1 | |
| SCHEMBL14400887 | 0.73 | TDP1 (0.39) | TSHRCYP3A4ALDH1A1RECQLTDP1 | |
| SCHEMBL4546456 | 0.73 | ALDH1A1 (0.40) | TSHRCYP3A4ALDH1A1RECQLTDP1 | |
| SCHEMBL27987226 | 0.73 | POLB (0.46) | ALDH1A1RECQLLMNAPOLBL3MBTL1 | |
| SCHEMBL27465806 | 0.72 | ALDH1A1 (0.39) | TSHRALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL801582 | 0.71 | CTSB (0.51) | TSHRCYP3A4ALDH1A1RECQLTDP1 | |
| Hydrochloric Acid SCHEMBL27537939 | 0.70 | CTSB (0.50) | TSHRCYP3A4ALDH1A1RECQLTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105814046-B | Imidazopyridine derivatives as TNF active regulators | UCB生物制药私人有限公司 | 2018-01-30 | — | — | CN | disclosed |
| CN-105814046-A | Imidazopyridine derivatives as modulators of TNF activity | UCB生物制药私人有限公司 | 2016-07-27 | — | — | CN | disclosed |