Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28467255 | 0.77 | CYP19A1 (0.43) | — | |
| SCHEMBL6019366 | 0.76 | POLB (0.64) | — | |
| SCHEMBL28082018 | 0.76 | MAPT (0.66) | — | |
| SCHEMBL1663493 | 0.75 | TAAR1 (0.59) | TAAR1SLC6A3KCNH2 | |
| SCHEMBL1662919 | 0.75 | TAAR1 (0.61) | TAAR1SLC6A3KCNH2 | |
| SCHEMBL2295355 | 0.75 | DRD2 (0.47) | — | |
| SCHEMBL2295207 | 0.75 | DRD2 (0.47) | — | |
| SCHEMBL5118709 | 0.75 | DRD2 (0.47) | — | |
| SCHEMBL931628 | 0.74 | NHERF1 (0.52) | — | |
| SCHEMBL28081980 | 0.74 | TP53 (0.69) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105820104-B | A kind of indoles -2- amides compound with anti-inflammatory effect and its application in preparing anti-inflammatory drugs | 温州医科大学 | 2018-12-11 | — | — | CN | disclosed |
| CN-105820104-A | Indole-2-acetamide compound with anti-inflammatory effect, and application thereof in preparation of anti-inflammatory drugs | 温州医科大学 | 2016-08-03 | — | — | CN | disclosed |