Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.66 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28082028 | 0.89 | HRH4 (0.62) | MAPTNPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL6019366 | 0.80 | POLB (0.64) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL931628 | 0.78 | NHERF1 (0.52) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL29732649 | 0.78 | MAPT (0.61) | MAPTGAANPC1RAB9AMEN1 | |
| SCHEMBL28775985 | 0.78 | MAPT (0.61) | MAPTGAANPC1RAB9AMEN1 | |
| SCHEMBL28081980 | 0.78 | TP53 (0.69) | MAPTGAANPC1RAB9AMEN1 | |
| SCHEMBL23258395 | 0.77 | MEN1 (0.57) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL7126991 | 0.77 | MEN1 (0.76) | MAPTNPC1MEN1KMT2AMAPK1 | |
| SCHEMBL28082015 | 0.76 | MAOA (0.59) | MAPTGAANPC1RAB9AMEN1 | |
| SCHEMBL28082050 | 0.76 | TAAR1 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105820104-B | A kind of indoles -2- amides compound with anti-inflammatory effect and its application in preparing anti-inflammatory drugs | 温州医科大学 | 2018-12-11 | — | — | CN | disclosed |
| CN-105820104-A | Indole-2-acetamide compound with anti-inflammatory effect, and application thereof in preparation of anti-inflammatory drugs | 温州医科大学 | 2016-08-03 | — | — | CN | disclosed |