Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | TTR | P02766 | 2/20 | 0.36 |
| ▸ | TPMT | P51580 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30806393 | 1.00 | KMT2A (0.42) | KMT2AALDH1A1HSPB1ATMTDP1 | |
| SCHEMBL28082067 | 1.00 | KMT2A (0.42) | KMT2AALDH1A1HSPB1ATMTDP1 | |
| SCHEMBL30806384 | 1.00 | KMT2A (0.42) | KMT2AALDH1A1HSPB1ATMTDP1 | |
| SCHEMBL28529013 | 0.87 | ALDH1A1 (0.38) | KMT2AALDH1A1SRD5A2MEN1TPMT | |
| SCHEMBL28533883 | 0.87 | ALDH1A1 (0.38) | KMT2AALDH1A1SRD5A2MEN1TTR | |
| SCHEMBL18305024 | 0.87 | ALDH1A1 (0.38) | KMT2AALDH1A1SRD5A2MEN1TTR | |
| SCHEMBL18304994 | 0.87 | ALDH1A1 (0.38) | KMT2AALDH1A1SRD5A2MEN1TPMT | |
| SCHEMBL28082061 | 0.87 | MAPT (0.42) | KMT2AALDH1A1HSPB1ATMTDP1 | |
| SCHEMBL28082062 | 0.87 | MAPT (0.42) | KMT2AALDH1A1HSPB1ATMTDP1 | |
| SCHEMBL18128032 | 0.86 | SRD5A2 (0.41) | KMT2AALDH1A1HSPB1ATMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105814054-A | Fused imidazole and pyrazole derivatives as modulators of TNF activity | UCB生物制药私人有限公司 | 2016-07-27 | — | — | CN | disclosed |