Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 2/20 | 0.35 |
| ▸ | CHRM1 known ✓ | P11229 | 2/20 | 0.35 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | GALR3 | O60755 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27770233 | 0.89 | MAPT (0.42) | MAPTSMN1; SMN2GALR3BLMTSHR | |
| SCHEMBL28095366 | 0.87 | TSHR (0.40) | MAPTSMN1; SMN2GALR3BLMTSHR | |
| Hydrochloric Acid SCHEMBL1238012 | 0.71 | MAPT (0.60) | MAPTSMN1; SMN2GALR3BLMTSHR | |
| Ammonia Solution, Strong SCHEMBL28166132 | 0.70 | TSHR (0.36) | TSHR | |
| SCHEMBL2946080 | 0.69 | TSHR (0.59) | MAPTSMN1; SMN2GALR3BLMTSHR | |
| SCHEMBL2424095 | 0.69 | TSHR (0.44) | SMN1; SMN2TSHR | |
| SCHEMBL3657429 | 0.69 | TSHR (0.44) | SMN1; SMN2TSHR | |
| Hydrochloric Acid SCHEMBL27882963 | 0.68 | MAPT (0.39) | MAPTSMN1; SMN2GALR3BLMTSHR | |
| SCHEMBL28321811 | 0.68 | TSHR (0.44) | TSHR | |
| SCHEMBL12492096 | 0.68 | TSHR (0.47) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105745230-A | Radical polymerization initiator and method for producing polymer | 日本瑞翁株式会社 | 2016-07-06 | — | — | CN | disclosed |