Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 2/20 | 0.57 |
| ▸ | CHRM1 known ✓ | P11229 | 2/20 | 0.57 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | GALR3 | O60755 | 1/20 | 0.60 |
| ▸ | BLM | P54132 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | TSHR | P16473 | 8/20 | 0.57 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.57 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.57 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2946080 | 0.98 | TSHR (0.59) | MAPTSMN1; SMN2GALR3BLMLMNA | |
| Bromide SCHEMBL28073958 | 0.96 | TSHR (0.57) | MAPTSMN1; SMN2GALR3BLMLMNA | |
| Sulfuric Acid SCHEMBL28170181 | 0.90 | TSHR (0.50) | MAPTSMN1; SMN2GALR3BLMLMNA | |
| SCHEMBL28038694 | 0.87 | TSHR (0.47) | MAPTSMN1; SMN2GALR3BLMLMNA | |
| SCHEMBL1406196 | 0.85 | TSHR (0.46) | MAPTSMN1; SMN2GALR3BLMLMNA | |
| Hydrochloric Acid SCHEMBL2988641 | 0.84 | MAPT (0.42) | MAPTSMN1; SMN2GALR3BLMLMNA | |
| Hydrochloric Acid SCHEMBL1667311 | 0.81 | TSHR (0.40) | MAPTSMN1; SMN2GALR3BLMLMNA | |
| SCHEMBL30803818 | 0.81 | TSHR (0.47) | MAPTSMN1; SMN2GALR3BLMLMNA | |
| Hydrochloric Acid SCHEMBL27770233 | 0.80 | MAPT (0.42) | MAPTSMN1; SMN2GALR3BLMLMNA | |
| SCHEMBL4632793 | 0.80 | TSHR (0.41) | MAPTSMN1; SMN2GALR3BLMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 261 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119912911-A | Anti-collapse wall-fixing material for drilling fluid for improving integrity of shaft and application | 中国石油天然气股份有限公司 | 2025-05-02 | — | — | CN | claimed |
| CN-114591720-B | Tackifier for high-temperature-resistant and saturated-salt-resistant drilling fluid and preparation method thereof | 中国石油化工股份有限公司 | 2023-05-30 | — | — | CN | claimed |
| CN-114591720-A | Tackifier for high-temperature-resistant and saturated salt-resistant drilling fluid and preparation method thereof | 中国石油化工股份有限公司 | 2022-06-07 | — | — | CN | claimed |
| EP-2203150-B1 | PERSONAL CARE COMPOSITIONS COMPRISING UNDECYL SULFATES | PROCTER & GAMBLE (US) | 2016-06-01 | — | — | EP | claimed |
| CN-105189589-A | Polymers prepared from alkoxylated polyamines | AKZO NOBEL CHEMICALS INT BV | 2015-12-23 | — | — | CN | claimed |
| EP-2203150-A2 | PERSONAL CARE COMPOSITIONS COMPRISING UNDECYL SULFATES | The Procter & Gamble Company (US) | 2010-07-07 | — | — | EP | claimed |
| US-20090155383-A1 | Personal Care Compositions Comprising Undecyl Sulfates | THE PROCTER & GAMBLE COMPANY | 2009-06-18 | — | — | US | claimed |
| WO-2009053931-A2 | PERSONAL CARE COMPOSITIONS COMPRISING UNDECYL SULFATES | THE PROCTER & GAMBLE COMPANY (US) | 2009-04-30 | — | — | WO | claimed |
| EP-2046847-A2 | POLYMERIC VISCOSITY MODIFIERS | The Procter and Gamble Company (US) | 2009-04-15 | — | — | EP | claimed |
| EP-2026849-A2 | CURABLE HYDROPHILIC COMPOSITIONS | 3M Innovative Properties Company (US) | 2009-02-25 | — | — | EP | claimed |
| WO-2008060677-A2 | CURABLE HYDROPHILIC COMPOSITIONS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2008-05-22 | — | — | WO | claimed |
| US-20080033129-A1 | Polymeric viscosity modifiers | THE PROCTER & GAMBLE COMPANY | 2008-02-07 | — | — | US | claimed |
| WO-2008015653-A2 | POLYMERIC VISCOSITY MODIFIERS | THE PROCTER & GAMBLE COMPANY (US) | 2008-02-07 | — | — | WO | claimed |
| US-20070275042-A1 | CURABLE HYDROPHILIC COMPOSITIONS | 3M INNOVATIVE PROPERTIES COMPANY | 2007-11-29 | — | — | US | claimed |
| US-7005143-B2 | Gel materials, medical articles, and methods | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2006-02-28 | — | — | US | claimed |
| EP-1494727-A1 | GEL MATERIALS, MEDICAL ARTICLES, AND METHODS | 3M Innovative Properties Company (US) | 2005-01-12 | — | — | EP | claimed |
| US-20030203011-A1 | Gel materials, medical articles, and methods | 3M INNOVATIVE PROPERTIES COMPANY | 2003-10-30 | — | — | US | claimed |
| WO-2003086493-A1 | GEL MATERIALS, MEDICAL ARTICLES, AND METHODS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2003-10-23 | — | — | WO | claimed |
| CN-119912911-A | Anti-collapse wall-fixing material for drilling fluid for improving integrity of shaft and application | 中国石油天然气股份有限公司 | 2025-05-02 | — | — | CN | disclosed |
| EP-0190499-A2 | Antistatic polymeric article | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-08-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030203011-A1 | Gel materials, medical articles, and methods | PTGES, PTGS2, PTGIS | CHRM2 4623/4885CHRM1 4744/4885CHRM3 4655/4885 |
| US-20090155383-A1 | Personal Care Compositions Comprising Undecyl Sulfates | USP25, UTS2R, USP30 | CHRM2 4703/4885CHRM1 4798/4885CHRM3 4559/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.