Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 6/20 | 0.48 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.38 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27776929 | 0.82 | NPC1 (0.50) | ALDH1A1ADORA2ANPC1MAPTMEN1 | |
| SCHEMBL26740722 | 0.80 | NPC1 (0.57) | ALDH1A1NPC1MAPTMEN1POLB | |
| SCHEMBL29663058 | 0.75 | ALDH1A1 (0.54) | TGFBR1ALDH1A1NPC1MAPTPOLB | |
| SCHEMBL4777973 | 0.74 | KDM4E (0.50) | ALDH1A1ADORA2ANPC1MAPTPOLB | |
| SCHEMBL28138772 | 0.74 | TGFBR1 (0.53) | TGFBR1ALDH1A1ADORA2ANPC1MAPT | |
| SCHEMBL3629022 | 0.74 | TLR8 (0.45) | ALDH1A1ADORA2AMEN1RAB9AKMT2A | |
| SCHEMBL16460200 | 0.73 | TGFBR1 (0.52) | TGFBR1ALDH1A1NPC1MAPTMEN1 | |
| SCHEMBL28507020 | 0.71 | CCNT1 (0.60) | ALDH1A1ADORA2ATLR8KDM4E | |
| SCHEMBL30507485 | 0.71 | CCNT1 (0.60) | ALDH1A1ADORA2ATLR8KDM4E | |
| SCHEMBL17195073 | 0.71 | TOP1 (0.56) | TGFBR1ALDH1A1ADORA2ANPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106083845-A | A kind of 1,5 naphthyridine type luminous organic material compounds and synthetic method thereof and application | 金陵科技学院 | 2016-11-09 | — | — | CN | disclosed |