Benzo[D]Thiazole

Benzo[D]Thiazole

SCHEMBL28083306

Nc1ccc([N+](=O)[O-])c2nonc12.c1ccc2scnc2c1

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.45
HSD17B10 Q99714 2/20 0.45
MEN1 O00255 8/20 0.43
KMT2A Q03164 8/20 0.43
GSTP1 P09211 6/20 0.43
GSTM2 P28161 6/20 0.43
IDO1 P14902 5/20 0.43
MYC P01106 3/20 0.43
USP2 O75604 3/20 0.42
KEAP1 Q14145 1/20 0.42
NFE2L2 Q16236 1/20 0.42
POLB P06746 3/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
HTT P42858 2/20 0.41
RECQL P46063 2/20 0.41
GAA P10253 1/20 0.41
CYP2D6 P10635 1/20 0.40
CYP2C9 P11712 1/20 0.40
HPGD P15428 1/20 0.40
ALOX15 P16050 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL306168 0.80 MEN1 (0.56) MEN1KMT2AGSTP1GSTM2IDO1
Nitrobenzene SCHEMBL27909966 0.73 ALDH1A1 (0.63) ALDH1A1HSD17B10MEN1KMT2AL3MBTL1
Benzo[D]Thiazole SCHEMBL28208335 0.71 ALDH1A1 (0.70) ALDH1A1HSD17B10MEN1KMT2AL3MBTL1
SCHEMBL7052057 0.71 GSTM2 (0.66) ALDH1A1HSD17B10MEN1KMT2AGSTP1
Benzo[D]Thiazole SCHEMBL2404928 0.70 ALDH1A1 (0.58) ALDH1A1HSD17B10MEN1KMT2AL3MBTL1
SCHEMBL7768311 0.69 MEN1 (0.46) ALDH1A1MEN1KMT2APOLBHTT
Benzo[D]Thiazole SCHEMBL10808313 0.69 ALDH1A1 (0.51) ALDH1A1HSD17B10MEN1KMT2AL3MBTL1
Benzo[D]Thiazole SCHEMBL10808308 0.69 ALDH1A1 (0.51) ALDH1A1HSD17B10MEN1KMT2AL3MBTL1
Benzo[D]Thiazole SCHEMBL27485138 0.67 ALDH1A1 (0.91) ALDH1A1HSD17B10IDO1L3MBTL1HPGD
Benzo[D]Thiazole SCHEMBL451685 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103502218-B Compounds and methods for for conjugating biomolecules 生命科技公司 2016-08-17 CN disclosed