SCHEMBL306168

SCHEMBL306168

Nc1ccc([N+](=O)[O-])c2nonc12

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 7/20 0.56
KMT2A Q03164 7/20 0.56
USP2 O75604 3/20 0.56
KEAP1 Q14145 1/20 0.56
NFE2L2 Q16236 1/20 0.56
GSTP1 P09211 6/20 0.55
GSTM2 P28161 6/20 0.55
IDO1 P14902 7/20 0.53
POLB P06746 2/20 0.53
TNNI3 P19429 1/20 0.53
TNNT2 P45379 1/20 0.53
TNNC1 P63316 1/20 0.53
MYC P01106 1/20 0.53
PSMD14 O00487 1/20 0.50
MAPT P10636 1/20 0.50
RXFP1 Q9HBX9 1/20 0.50
G6PD P11413 1/20 0.49
CASP6 P55212 1/20 0.49
GAA P10253 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7052057 0.88 GSTM2 (0.66) MEN1KMT2AUSP2GSTP1GSTM2
SCHEMBL1932562 0.81 GSTP1 (0.48) MEN1KMT2AGSTP1GSTM2IDO1
Benzo[D]Thiazole SCHEMBL28083306 0.80 ALDH1A1 (0.45) MEN1KMT2AUSP2KEAP1NFE2L2
SCHEMBL2608494 0.79 GSTP1 (0.61) MEN1KMT2AUSP2GSTP1GSTM2
SCHEMBL8788868 0.78 GSTP1 (0.49) MEN1KMT2AUSP2GSTP1GSTM2
SCHEMBL3047621 0.78 MEN1 (0.60) MEN1KMT2AUSP2GSTP1GSTM2
SCHEMBL3192786 0.78 IDO1 (0.57) MEN1KMT2AUSP2GSTP1GSTM2
SCHEMBL18878880 0.78 GSTM2 (0.55) MEN1KMT2AUSP2GSTP1GSTM2
SCHEMBL315294 0.78 IDO1 (0.57) MEN1KMT2AUSP2GSTP1GSTM2
SCHEMBL41754 0.78 IDO1 (0.58) MEN1KMT2AUSP2GSTP1GSTM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119998395-A Two-component composition based on epoxide mixtures 汉高股份有限及两合公司 2025-05-13 CN claimed
CN-119757717-A Multiple aptamer sensor for detecting novel psychoactive substances and application thereof 山西医科大学 2025-04-04 CN claimed
WO-2024168209-A2 CONJUGATED METABOLITES FOR CANCER DETECTION AND TREATMENT VANDERBILT UNIVERSITY (US) 2024-08-15 WO claimed
CN-115925803-B Lighting GPx4 fluorescent molecular probe and application thereof 华中科技大学 2024-05-14 CN claimed
CN-117903044-A Pyridine-2-alkynyl carbonyl compound and preparation method and application thereof 华中师范大学 2024-04-19 CN claimed
US-11927593-B2 High-throughput single molecule protein identification THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2024-03-12 US claimed
EP-3507603-B1 COMPOSITIONS AND METHODS FOR ENHANCED FLUORESCENCE LIFE TECHNOLOGIES CORP (US) 2024-03-06 EP claimed
WO-2023164252-A1 ISOTHERMAL NUCLEIC ACID DETECTION ASSAYS AND USES THEREOF TRUSTEES OF BOSTON UNIVERSITY (US) 2023-08-31 WO claimed
CN-115925803-A Lighting type GPx4 fluorescent molecular probe and application thereof 华中科技大学 2023-04-07 CN claimed
CN-115704773-A Multicolor immunofluorescent staining method and imaging method 佰诺全景生物技术(北京)有限公司 2023-02-17 CN claimed
US-20010043495-A1 Three dimensional optical memory storage XEROX CORPORATION 2001-11-22 US claimed
WO-2001067176-A1 THREE DIMENSIONAL OPTICAL MEMORY STORAGE XEROX CORPORATION (US) 2001-09-13 WO claimed
EP-1090073-A1 XANTHENE DYES AND THEIR APPLICATION AS LUMINESCENCE QUENCHING COMPOUNDS Molecular Probes Inc. (US) 2001-04-11 EP claimed
US-6214500-B1 Core and shell matrix compositions and processes XEROX CORPORATION 2001-04-10 US claimed
WO-2000064988-A1 XANTHENE DYES AND THEIR APPLICATION AS LUMINESCENCE QUENCHING COMPOUNDS MOLECULAR PROBES, INC. (US) 2000-11-02 WO claimed
US-5952131-A Core and shell matrix compositions and processes XEROX CORPORATION (US) 1999-09-14 US claimed
US-5773236-A FLUORESCENT DYES FOR DETECTION OF ENZYMES FOR METABOLISM IN CELLS MOLECULE PROBES, INC. (US) 1998-06-30 US claimed
EP-0468470-B1 Benzimidazoles, medicaments containing them and process for their preparation THOMAE GMBH DR K (DE) 1997-04-16 EP claimed
US-4576745-A Method for the fluorimetric determination of endotoxins, new peptides carrying a fluorophorous substance usable in said method and method for its preparation CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 1986-03-18 US claimed
EP-0056210-B1 METHOD FOR THE FLUORIMETRIC DETERMINATION OF ENDOTOXINS, PEPTIDES CONTAINING A FLUOROPHORE USED IN THE SAID METHOD AND THEIR METHOD OF PREPARATION CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 1986-03-12 EP claimed