Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.36 |
| ▸ | CA1 | P00915 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 4/20 | 0.35 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7207177 | 0.92 | CA2 (0.41) | CA2CA1LMNAFAAHMAPK1 | |
| SCHEMBL28609396 | 0.86 | FAAH (0.42) | CA2CA1LMNAFAAHCNR1 | |
| SCHEMBL31112794 | 0.83 | LMNA (0.47) | CA1LMNAFAAHCNR1CNR2 | |
| SCHEMBL31112560 | 0.81 | LMNA (0.50) | CA1LMNAFAAHCNR1CNR2 | |
| SCHEMBL31112876 | 0.81 | LMNA (0.50) | CA1LMNAFAAHCNR1CNR2 | |
| SCHEMBL28662288 | 0.81 | FAAH (0.44) | CA2CA1LMNAFAAHMAPK1 | |
| SCHEMBL27617573 | 0.79 | CA2 (0.38) | CA2CA1FAAHMAPK1CTSK | |
| SCHEMBL1463204 | 0.79 | CHRM1 (0.39) | CA2CA1LMNAFAAHCTSK | |
| SCHEMBL11369135 | 0.78 | ZDHHC7 (0.47) | CA2CA1LMNAFAAHCNR1 | |
| SCHEMBL28005991 | 0.78 | CA2 (0.41) | CA2CA1LMNAFAAHMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103626765-B | Substituted azaindole compounds and salt, compositions and purposes | 广东东阳光药业有限公司 | 2016-08-10 | — | — | CN | disclosed |