Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.31 |
| ▸ | HTR1A known ✓ | P08908 | 1/20 | 0.31 |
| ▸ | ADRA2A known ✓ | P08913 | 1/20 | 0.31 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 known ✓ | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28096521 | 0.98 | CHRM2 (0.32) | CHRM2HTR1AADRA2AADORA3CHRM1 | |
| SCHEMBL27747710 | 0.92 | — | — | |
| SCHEMBL28096063 | 0.89 | CA1 (0.31) | — | |
| Aspartic Acid SCHEMBL28115417 | 0.82 | SLC1A2 (0.41) | — | |
| SCHEMBL28286474 | 0.82 | OPRM1 (0.34) | OPRM1 | |
| Bromide SCHEMBL28179417 | 0.80 | — | — | |
| SCHEMBL3772638 | 0.79 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL3772292 | 0.78 | GLB1 (0.31) | — | |
| SCHEMBL27942968 | 0.77 | — | — | |
| SCHEMBL27700944 | 0.77 | GLB1 (0.32) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109126392-A | It is a kind of that CO in flue gas is carried out using ionic liquid2The device and technique of trapping | 北京化工大学 | 2019-01-04 | — | — | CN | claimed |
| CN-106478512-A | A kind of zinc-base glyoxaline ion liquid for fluid-tight and preparation method thereof | 林州市科能材料科技有限公司 | 2017-03-08 | — | — | CN | claimed |
| CN-119236617-A | Device and method for capturing carbon dioxide by using supergravity coupling in-situ organic steam stripping reinforced ionic liquid | 郑州中科新兴产业技术研究院 | 2025-01-03 | — | — | CN | disclosed |
| CN-109126392-A | It is a kind of that CO in flue gas is carried out using ionic liquid2The device and technique of trapping | 北京化工大学 | 2019-01-04 | — | — | CN | disclosed |
| CN-106478512-A | A kind of zinc-base glyoxaline ion liquid for fluid-tight and preparation method thereof | 林州市科能材料科技有限公司 | 2017-03-08 | — | — | CN | disclosed |
| CN-106045913-A | Imidazolium perrhenate ionic liquid with amino groups as well as preparation method and application of imidazolium perrhenate ionic liquid | 辽宁大学 | 2016-10-26 | — | — | CN | disclosed |
| CN-105949129-A | Imidazolium bromide ionic liquid containing amine groups and preparation method and application of ionic liquid | 辽宁大学 | 2016-09-21 | — | — | CN | disclosed |
| CN-105836731-A | Carbon nano tube modified by functionalized ionic liquid and method for immobilizing lipase by using carbon nano tube | 南京工业大学 | 2016-08-10 | — | — | CN | disclosed |