Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER2 | P43116 | 11/20 | 0.40 |
| ▸ | PTGER3 | P43115 | 5/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | PTGDR | Q13258 | 6/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28084590 | 1.00 | PTGER2 (0.40) | PTGER2PTGER3PDGFRBFGFR1KDR | |
| SCHEMBL27959330 | 0.75 | LMNA (0.43) | PTGER2PTGER3PDGFRBFGFR1KDR | |
| SCHEMBL27959331 | 0.75 | LMNA (0.43) | PTGER2PTGER3PDGFRBFGFR1KDR | |
| SCHEMBL25416662 | 0.74 | ALDH1A1 (0.42) | CYP19A1KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL30912507 | 0.74 | ALDH1A1 (0.42) | CYP19A1KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL30912518 | 0.74 | ALDH1A1 (0.42) | CYP19A1KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL849497 | 0.74 | TSHR (0.38) | PTGER2PTGER3PDGFRBFGFR1KDR | |
| SCHEMBL849498 | 0.74 | TSHR (0.38) | PTGER2PTGER3PDGFRBFGFR1KDR | |
| SCHEMBL27959528 | 0.71 | KMT2A (0.36) | PTGER2PTGER3CYP19A1KDM4EMEN1 | |
| SCHEMBL16422287 | 0.68 | TDP1 (0.44) | PTGER2PTGER3PTGDRMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103848814-B | The full ketone derivatives of substituted indole as tyrosine kinase inhibitor | 山东亨利医药科技有限责任公司 | 2016-08-17 | — | — | CN | disclosed |