Hydrogen Sulfide

Hydrogen Sulfide

SCHEMBL28084602

CC(=O)c1ccc(S(=O)(=O)c2ccccc2)cc1.S

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.71
LMNA P02545 3/20 0.71
KMT2A Q03164 2/20 0.71
KDM4E B2RXH2 1/20 0.71
MAPK1 P28482 1/20 0.71
CA12 O43570 1/20 0.59
CA9 Q16790 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.57
HTR6 P50406 1/20 0.56
SMN1; SMN2 Q16637 4/20 0.55
HPGD P15428 4/20 0.54
MEN1 O00255 1/20 0.54
ALDH1A1 P00352 3/20 0.54
GAA P10253 2/20 0.54
NPC1 O15118 1/20 0.51
RAB9A P51151 1/20 0.51
TP53 P04637 1/20 0.51
THRB P10828 1/20 0.51
NAMPT P43490 1/20 0.49
PKM P14618 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5387372 0.98 MAPT (0.73) MAPTLMNAKMT2AKDM4EMAPK1
SCHEMBL4027167 0.89 MAPT (0.61) MAPTLMNAKMT2AKDM4EMAPK1
SCHEMBL18364472 0.86 KMT2A (0.58) MAPTLMNAKMT2AKDM4EMAPK1
SCHEMBL10870974 0.84 HPGD (0.77) MAPTLMNAKMT2AKDM4EMAPK1
(Phenylsulfonyl)Benzene SCHEMBL29058880 0.83 HTR6 (0.74) MAPTLMNAKMT2AKDM4EMAPK1
(Phenylsulfonyl)Benzene SCHEMBL2381369 0.83 HTR6 (0.74) MAPTLMNAKMT2AKDM4EMAPK1
SCHEMBL3773485 0.82 GAA (0.67) MAPTLMNAKMT2AKDM4EMAPK1
SCHEMBL7938512 0.82 HSD17B1 (0.63) MAPTLMNAKMT2AKDM4EMAPK1
SCHEMBL165237 0.81 HTR6 (0.64) MAPTLMNAKMT2ACA12CA9
SCHEMBL24360902 0.81 CA12 (0.70) MAPTLMNAKMT2AKDM4EMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107108955-B It can rear curing rubber class contact adhesive 3M创新有限公司 2019-03-01 CN disclosed
CN-107108955-A Can solidify afterwards rubber-like contact adhesive 3M创新有限公司 2017-08-29 CN disclosed
CN-105829468-A Post-curable pressure sensitive adhesives 3M创新有限公司 2016-08-03 CN disclosed