SCHEMBL28085202

SCHEMBL28085202

NC(=O)OC(C(O)C=O)C(O)C(O)CO

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.36
SLCO1B1 Q9Y6L6 1/20 0.36
LMNA P02545 2/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
PDE4A P27815 1/20 0.34
TDP1 Q9NUW8 1/20 0.33
AKR1B1 P15121 1/20 0.31
MPI P34949 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5685647 1.00 USP2 (0.36) USP2SLCO1B1LMNAL3MBTL1PDE4A
Phosphoric Acid SCHEMBL28643541 0.94 MPI (0.38) USP2SLCO1B1LMNAL3MBTL1PDE4A
SCHEMBL770242 0.79 LMNA (0.39) USP2SLCO1B1LMNAL3MBTL1PDE4A
SCHEMBL10713437 0.79 LMNA (0.39) USP2SLCO1B1LMNAL3MBTL1PDE4A
SCHEMBL2635169 0.79 LMNA (0.39) USP2SLCO1B1LMNAL3MBTL1PDE4A
SCHEMBL9814278 0.79 TSHR (0.32) USP2SLCO1B1LMNAL3MBTL1PDE4A
SCHEMBL6226136 0.79 PDE4A (0.32) USP2SLCO1B1LMNAL3MBTL1PDE4A
SCHEMBL21596441 0.78 USP2 (0.38) USP2SLCO1B1LMNAL3MBTL1PDE4A
SCHEMBL9488106 0.77 TSHR (0.33) LMNAL3MBTL1PDE4A
SCHEMBL6228481 0.77 MAPT (0.36) LMNAL3MBTL1PDE4AAKR1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108948106-B Preparation method of 2-hydroxy gulose receptor derivative, bleomycin disaccharide and precursor thereof 广州中医药大学(广州中医药研究院) 2021-08-10 CN claimed
CN-108794547-B Preparation method of 3-O-carbamyl mannose donor derivative, bleomycin disaccharide and precursor thereof 广州中医药大学(广州中医药研究院) 2021-08-10 CN claimed
CN-105693787-A 3-O-ammonia formyl mannose derivative containing alkynyl and preparation method and application of 3-O-ammonia formyl mannose derivative 华东师范大学 2016-06-22 CN claimed
CN-108948106-B Preparation method of 2-hydroxy gulose receptor derivative, bleomycin disaccharide and precursor thereof 广州中医药大学(广州中医药研究院) 2021-08-10 CN disclosed
CN-108794547-B Preparation method of 3-O-carbamyl mannose donor derivative, bleomycin disaccharide and precursor thereof 广州中医药大学(广州中医药研究院) 2021-08-10 CN disclosed
CN-108794547-B Preparation method of 3-O-carbamyl mannose donor derivative, bleomycin disaccharide and precursor thereof 广州中医药大学(广州中医药研究院) 2021-08-10 CN disclosed
CN-108794547-B Preparation method of 3-O-carbamyl mannose donor derivative, bleomycin disaccharide and precursor thereof 广州中医药大学(广州中医药研究院) 2021-08-10 CN disclosed
CN-105693787-A 3-O-ammonia formyl mannose derivative containing alkynyl and preparation method and application of 3-O-ammonia formyl mannose derivative 华东师范大学 2016-06-22 CN disclosed