Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | MPI | P34949 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28085202 | 1.00 | USP2 (0.36) | USP2SLCO1B1LMNAL3MBTL1PDE4A | |
| Phosphoric Acid SCHEMBL28643541 | 0.94 | MPI (0.38) | USP2SLCO1B1LMNAL3MBTL1PDE4A | |
| SCHEMBL770242 | 0.79 | LMNA (0.39) | USP2SLCO1B1LMNAL3MBTL1PDE4A | |
| SCHEMBL10713437 | 0.79 | LMNA (0.39) | USP2SLCO1B1LMNAL3MBTL1PDE4A | |
| SCHEMBL2635169 | 0.79 | LMNA (0.39) | USP2SLCO1B1LMNAL3MBTL1PDE4A | |
| SCHEMBL9814278 | 0.79 | TSHR (0.32) | USP2SLCO1B1LMNAL3MBTL1PDE4A | |
| SCHEMBL6226136 | 0.79 | PDE4A (0.32) | USP2SLCO1B1LMNAL3MBTL1PDE4A | |
| SCHEMBL21596441 | 0.78 | USP2 (0.38) | USP2SLCO1B1LMNAL3MBTL1PDE4A | |
| SCHEMBL9488106 | 0.77 | TSHR (0.33) | LMNAL3MBTL1PDE4A | |
| SCHEMBL6228481 | 0.77 | MAPT (0.36) | LMNAL3MBTL1PDE4AAKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108794547-B | Preparation method of 3-O-carbamyl mannose donor derivative, bleomycin disaccharide and precursor thereof | 广州中医药大学(广州中医药研究院) | 2021-08-10 | — | — | CN | claimed |
| CN-108948106-B | Preparation method of 2-hydroxy gulose receptor derivative, bleomycin disaccharide and precursor thereof | 广州中医药大学(广州中医药研究院) | 2021-08-10 | — | — | CN | claimed |
| CN-105693787-A | 3-O-ammonia formyl mannose derivative containing alkynyl and preparation method and application of 3-O-ammonia formyl mannose derivative | 华东师范大学 | 2016-06-22 | — | — | CN | claimed |
| US-RE30413-E | ANTIBIOTICS; ANTITUMOR AGENTS | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1980-10-07 | — | — | US | claimed |
| US-3932374-A | ANTITUMOR AGENTS | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JA) | 1976-01-13 | — | — | US | claimed |
| CN-108794547-B | Preparation method of 3-O-carbamyl mannose donor derivative, bleomycin disaccharide and precursor thereof | 广州中医药大学(广州中医药研究院) | 2021-08-10 | — | — | CN | disclosed |
| CN-108794547-B | Preparation method of 3-O-carbamyl mannose donor derivative, bleomycin disaccharide and precursor thereof | 广州中医药大学(广州中医药研究院) | 2021-08-10 | — | — | CN | disclosed |
| CN-108794547-B | Preparation method of 3-O-carbamyl mannose donor derivative, bleomycin disaccharide and precursor thereof | 广州中医药大学(广州中医药研究院) | 2021-08-10 | — | — | CN | disclosed |
| CN-108948106-B | Preparation method of 2-hydroxy gulose receptor derivative, bleomycin disaccharide and precursor thereof | 广州中医药大学(广州中医药研究院) | 2021-08-10 | — | — | CN | disclosed |
| CN-105693787-A | 3-O-ammonia formyl mannose derivative containing alkynyl and preparation method and application of 3-O-ammonia formyl mannose derivative | 华东师范大学 | 2016-06-22 | — | — | CN | disclosed |
| EP-1086241-B1 | NON-VIABLE CELL PREPARATION AND ASSAY REAGENT | AZUR ENVIRONMENTAL LTD (GB) | 2006-03-29 | — | — | EP | disclosed |
| US-6524810-B2 | Making a non-viable preparation of cells by the addition of bleomycin/phleomycin anitibiotics which retains signal-generating metabolic activity such as bioluminescence | AZUR ENVIRONMENTAL | 2003-02-25 | — | — | US | disclosed |
| EP-0135675-B1 | NOVEL 3-(4'-AMINOBUTYLAMINO)-PROPYLAMINO-BLEOMYCIN DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 1988-02-17 | — | — | EP | disclosed |
| US-4568490-A | REDUCTIVE CONDENSATION WITH A CARBONYL COMPOUND | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1986-02-04 | — | — | US | disclosed |
| US-4537880-A | Aminopropylaminobleomycin derivatives and process for preparation thereof | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1985-08-27 | — | — | US | disclosed |
| US-RE30451-E | ANTITUMOR AGENTS | Zaidan Jojin Biseibutsu Kagaku Kenkyu Kai (JP) | 1980-12-16 | — | — | US | disclosed |
| US-RE30413-E | ANTIBIOTICS; ANTITUMOR AGENTS | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1980-10-07 | — | — | US | disclosed |
| US-RE30413-E | ANTIBIOTICS; ANTITUMOR AGENTS | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1980-10-07 | — | — | US | disclosed |
| US-3932374-A | ANTITUMOR AGENTS | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JA) | 1976-01-13 | — | — | US | disclosed |
| US-3867257-A | Bleomycinic acid and process for preparing thereof | MICROBIAL CHEM RES FOUND | 1975-02-18 | — | — | US | disclosed |